Transcatheter aortic valve replacement is now indicated across all risk categories of patients
with symptomatic severe aortic stenosis and has been proposed as first line option for the …

Transcatheter aortic valve replacement (TAVR) has the advantages of less trauma and faster
postoperative recovery, which has brought the possibility to the elderly patient with valvular …

Materials currently used to repair or replace a heart valve are not durable. Their limited
durability related to structural degeneration or thrombus formation is attributed to their …

Extracellular matrix (ECM) is an active player in cardiovascular calcification (CVC), a major
public health issue with an unmet need for effective therapies. Lysyl oxidase (LOX) …

Abstract Development of tissue engineered scaffolds for cardiac valve replacement is
nearing clinical translation. While much work has been done to characterize mechanical …

Valvular heart disease (VHD) has become a burden and a growing public health problem in
humans, causing significant morbidity and mortality worldwide. An increasing number of …

Due to the increasing aging population and the advancements in transcatheter aortic valve
replacement (TAVR), the use of bioprosthetic heart valves (BHVs) in patients diagnosed with …

Pliable microfibrous, bioresorbable elastomeric heart valve prostheses are investigated in
search of sustainable heart valve replacement. These cell-free implants recruit cells and …

Injury to cardiac valves is a major contributor to mortality associated with cardiovascular
diseases. Artificial valves are preferred for their mimicry of natural valve efficiency in …

Bioprosthetic heart valves (BHV) fabricated from glutaraldehyde-fixed heterograft tissue,
such as bovine pericardium (BP), are widely used for treating heart valve disease, a group of …