BACKGROUND Infertility is a major issue in human reproductive health, affecting an
estimated 15% of couples worldwide. Infertility can result from disorders of sex development …

Spermatozoa contain highly specialized structural features reflecting unique functions
required for fertilization. Among them, the flagellum is a sperm-specific organelle required to …

Sperm malformation is a direct factor for male infertility. Multiple morphological abnormalities
of the flagella (MMAF), a severe form of asthenoteratozoospermia, are characterized by …

Despite the high prevalence of male infertility, very little is known about its etiology. In recent
years however, advances in gene sequencing technology have enabled us to identify a …

Asthenozoospermia (AZS), defined by reduced motility or absent sperm motility, is one of the
main causes of male infertility. This condition may be divided into isolated AZS in the …

STUDY QUESTION What are the causative genetic variants in patients with male infertility
due to severe sperm motility disorders? SUMMARY ANSWER We identified high confidence …

Background Genetic progress for fertility and reproduction traits in dairy cattle has been
limited due to the low heritability of most indicator traits. Moreover, most of the quantitative …

Sperm carries male genetic information, and flagella help move the sperm to reach oocytes.
When the ultrastructure of the flagella is abnormal, the sperm is unable to reach the oocyte …

Abstract Infertility affects 8–12% of couples globally, and the male factor is a primary cause
in~ 50% of couples. Male infertility is a multifactorial reproductive disorder, which can be …

Motile cilia and flagellar defects can result in primary ciliary dyskinesia, which is a
multisystemic genetic disorder that affects roughly 1: 10 000 individuals. The nexin-dynein …