The cytoskeleton and its components—actin, microtubules and intermediate filaments—
have been studied for decades, and multiple roles of the individual cytoskeletal …

Mercury (Hg) is a persistent bio-accumulative toxic metal with unique physicochemical
properties of public health concern since their natural and anthropogenic diffusions still …

Actin has well established functions in cellular morphogenesis. However, it is not well
understood how the various actin assemblies in a cell are kept in a dynamic equilibrium, in …

Cell adhesion to the extracellular matrix is essential for cellular processes, such as migration
and invasion. In response to cues from the microenvironment, integrin-mediated adhesions …

Microtubules (MT) and actin microfilaments are dynamic cytoskeleton components involved
in a range of intracellular processes. MTs play a role in cell division, beating of cilia and …

Microtubules are cytoskeletal elements known as drivers of directed cell migration, vesicle
and organelle trafficking, and mitosis. In this review, we discuss new research in the lens …

Integrins engage components of the extracellular matrix, and in collaboration with other
receptors, regulate signaling cascades that impact cell behavior in part by modulating the …

Cancer and chronic infections often increase levels of the bioactive lipid, lysophosphatidic
acid (LPA), that we have demonstrated acts as an inhibitory ligand upon binding LPAR5 on …

Exocytosis is a fundamental cellular process whereby secreted molecules are packaged into
vesicles that move along cytoskeletal filaments and fuse with the plasma membrane. To …

We provide guidelines for using statistical methods to analyze the types of experiments
reported in cellular and molecular biology journals such as Molecular Biology of the Cell …