Patients require mechanical ventilatory support when the ventilatory and/or gas exchange
capabilities of their respiratory system fail. This failure can be the result of processes both …

Improved gas exchange has been observed during spontaneous breathing with airway
pressure release ventilation (APRV) as compared with controlled mechanical ventilation …

Background. Patients with acute exacerbations of chronic obstructive pulmonary disease
may require endotracheal intubation with mechanical ventilation. We designed, and here …

That positive-pressure mechanical ventilation can save lives was proved during the
poliomyelitis epidemics of the 1950s1. Since that time there has been a growing increase in …

Tracheotomy is widely performed on ventilator-dependent patients, but its effects on
respiratory mechanics have not been studied. We measured the work of breathing (WOB) in …

We have previously shown (Am. J. Respir. Crit. Care Med. 1995; 152: 1248–1255) that in
patients needing mechanical ventilation, the load imposed on the inspiratory muscles is …

Objective: We tested whether the continuous monitoring of dynamic compliance could
become a useful bedside tool for detecting the beginning of collapse of a fully recruited lung …

When used in patients free of previous cardiorespiratory disease, mechanical ventilation
with a normal tidal volume does not have any discernible hemodynamic consequences …

We quantified inspiratory effort during patient-triggered ventilator cycles in 20 critically ill
patients receiving assisted mechanical ventilation (AMV). An index of the patient's work per …

Dynamic hyperinflation and intrinsic positive end-expiratory pressure (PEEPi) are observed
in patients with chronic obstructive pulmonary disease (COPD) and flow limitation. Several …