Au/Ag-cocatalyzed aldoximes to amides rearrangement under solvent-and acid-free conditions
RS Ramon, J Bosson, S Diez-Gonzalez… - The Journal of …, 2010 - ACS Publications
The gold/silver-cocatalyzed conversion of aldoximes into primary amides is reported. The
reaction, which proceeds under neat and acid-free conditions, allows for the conversion of a …
reaction, which proceeds under neat and acid-free conditions, allows for the conversion of a …
Design, synthesis, biological evaluation, and structure–activity relationships of substituted phenyl 4-(2-oxoimidazolidin-1-yl) benzenesulfonates as new tubulin …
Sixty-one phenyl 4-(2-oxoimidazolidin-1-yl) benzenesulfonates (PIB-SOs) and 13 of their
tetrahydro-2-oxopyrimidin-1 (2 H)-yl analogues (PPB-SOs) were prepared and biologically …
tetrahydro-2-oxopyrimidin-1 (2 H)-yl analogues (PPB-SOs) were prepared and biologically …
Activation of Neurogenesis in Multipotent Stem Cells Cultured In Vitro and in the Spinal Cord Tissue After Severe Injury by Inhibition of Glycogen Synthase Kinase-3
FJ Rodriguez-Jimenez, A Vilches, MA Perez-Arago… - …, 2021 - Springer
The inhibition of glycogen synthase kinase-3 (GSK-3) can induce neurogenesis, and the
associated activation of Wnt/β-catenin signaling via GSK-3 inhibition may represent a means …
associated activation of Wnt/β-catenin signaling via GSK-3 inhibition may represent a means …
Controlled generation and use of CO in flow
A method for the generation and use of carbon monoxide in flow chemistry has been
developed. By using a tube-in-tube reactor, oxalyl chloride can be conveniently and safely …
developed. By using a tube-in-tube reactor, oxalyl chloride can be conveniently and safely …
Styryl-N-phenyl-N′-(2-chloroethyl) ureas and styrylphenylimidazolidin-2-ones as new potent microtubule-disrupting agents using combretastatin A-4 as model
M Gagné-Boulet, S Fortin, J Lacroix… - European Journal of …, 2015 - Elsevier
Abstract Combretastatin A-4 (CA-4) is a well-studied and attractive molecular template to
develop new antimitotics. Several thousand of modifications were performed on the ring B …
develop new antimitotics. Several thousand of modifications were performed on the ring B …
Synthesis, Biological Evaluation, and Structure–Activity Relationships of Novel Substituted N-Phenyl Ureidobenzenesulfonate Derivatives Blocking Cell Cycle …
V Turcotte, S Fortin, F Vevey, Y Coulombe… - Journal of medicinal …, 2012 - ACS Publications
Twenty-eight new substituted N-phenyl ureidobenzenesulfonate (PUB-SO) and 18 N-
phenylureidobenzenesulfonamide (PUB-SA) derivatives were prepared. Several PUB-SOs …
phenylureidobenzenesulfonamide (PUB-SA) derivatives were prepared. Several PUB-SOs …
Synthesis, antiproliferative activity evaluation and structure–activity relationships of novel aromatic urea and amide analogues of N-phenyl-N′-(2-chloroethyl) ureas
Seven subsets of aromatic urea and amide analogues of N-phenyl-N′-(2-chloroethyl)
ureas (CEU) have been synthesized by nucleophilic addition of 3-chloropropylisocyanate, 2 …
ureas (CEU) have been synthesized by nucleophilic addition of 3-chloropropylisocyanate, 2 …
Synthesis, spectral, characterization, and anticancer activity of some binary and mixed ligand complexes of 4-methyl-2-pentanone thiosemicarbazone and some …
NS Youssef, EA El Zahany, MM Ali - Phosphorus, Sulfur, and …, 2010 - Taylor & Francis
The Schiff base ligand 4-methyl-2-pentanone thiosemicarbazone (MPTSC)(HL) has been
synthesized by the interaction of 4-methyl-2-pentanone (MP) and thiosemicarbazone (TSC) …
synthesized by the interaction of 4-methyl-2-pentanone (MP) and thiosemicarbazone (TSC) …
Synthesis and biological activities of new di-and trimeric quinoline derivatives
S Broch, H Hénon, AL Debaud, ML Fogeron… - Bioorganic & medicinal …, 2010 - Elsevier
The synthesis of non-peptidic helix mimetics based on a trimeric quinoline scaffold is
described. The ability of these new compounds, as well as their synthetic dimeric …
described. The ability of these new compounds, as well as their synthetic dimeric …
Synthesis and biological evaluation of novel N-phenyl ureidobenzenesulfonate derivatives as potential anticancer agents. Part 2. Modulation of the ring B
M Gagné-Boulet, H Moussa, J Lacroix, MF Côté… - European Journal of …, 2015 - Elsevier
DNA double strand-breaks (DSBs) are the most deleterious lesions that can affect the
genome of living beings and are lethal if not quickly and properly repaired. Recently, we …
genome of living beings and are lethal if not quickly and properly repaired. Recently, we …