Childhood adversity and neural development: A systematic review
KA McLaughlin, D Weissman… - Annual review of …, 2019 - annualreviews.org
An extensive literature on childhood adversity and neurodevelopment has emerged over the
past decade. We evaluate two conceptual models of adversity and neurodevelopment—the …
past decade. We evaluate two conceptual models of adversity and neurodevelopment—the …
[HTML][HTML] Amygdala circuit substrates for stress adaptation and adversity
Brain systems that promote the maintenance of homeostasis in face of stress have
significant adaptive value. A growing body of work across species demonstrates a critical …
significant adaptive value. A growing body of work across species demonstrates a critical …
Depression in neurodegenerative diseases: Common mechanisms and current treatment options
CPC Galts, LEB Bettio, DC Jewett, CC Yang… - Neuroscience & …, 2019 - Elsevier
Major depressive disorder (MDD) is a highly prevalent psychiatric disorder and a major
cause of disability worldwide. This neurological condition is commonly associated with …
cause of disability worldwide. This neurological condition is commonly associated with …
A review of vulnerability and risks for schizophrenia: Beyond the two hit hypothesis
Schizophrenia risk has often been conceptualized using a model which requires two hits in
order to generate the clinical phenotype—the first as an early priming in a genetically …
order to generate the clinical phenotype—the first as an early priming in a genetically …
Chronic stress weakens connectivity in the prefrontal cortex: architectural and molecular changes
E Woo, LH Sansing, AFT Arnsten, D Datta - Chronic Stress, 2021 - journals.sagepub.com
Chronic exposure to uncontrollable stress causes loss of spines and dendrites in the
prefrontal cortex (PFC), a recently evolved brain region that provides top-down regulation of …
prefrontal cortex (PFC), a recently evolved brain region that provides top-down regulation of …
Chronic stress and brain plasticity: mechanisms underlying adaptive and maladaptive changes and implications for stress-related CNS disorders
Stress responses entail neuroendocrine, autonomic, and behavioral changes to promote
effective coping with real or perceived threats to one's safety. While these responses are …
effective coping with real or perceived threats to one's safety. While these responses are …
[HTML][HTML] The etiology of poststroke-depression: a hypothesis involving HPA axis
L Zhou, T Wang, Y Yu, M Li, X Sun, W Song… - Biomedicine & …, 2022 - Elsevier
Approximately, one in three ischemic stroke survivors suffered from depression, namely,
post-stroke depression (PSD). PSD affects functional rehabilitation and may lead to poor …
post-stroke depression (PSD). PSD affects functional rehabilitation and may lead to poor …
Exercise and BDNF reduce Aβ production by enhancing α‐secretase processing of APP
SM Nigam, S Xu, JS Kritikou, K Marosi… - Journal of …, 2017 - Wiley Online Library
Alzheimer's disease (AD) is an age‐related neurodegenerative disorder characterized by
aggregation of toxic forms of amyloid β peptide (Aβ). Treatment strategies have largely been …
aggregation of toxic forms of amyloid β peptide (Aβ). Treatment strategies have largely been …
Understanding heterogeneity in grey matter research of adults with childhood maltreatment—A meta-analysis and review
C Paquola, MR Bennett, J Lagopoulos - Neuroscience & Biobehavioral …, 2016 - Elsevier
Childhood trauma has been associated with long term effects on prefrontal-limbic grey
matter. A literature search was conducted to identify structural magnetic resonance imaging …
matter. A literature search was conducted to identify structural magnetic resonance imaging …
A systematic review and meta-analysis of magnetic resonance imaging measurement of structural volumes in posttraumatic stress disorder
Posttraumatic stress disorder (PTSD) is a debilitating condition associated with mild to
moderate cognitive impairment and with a prevalence rate of up to 22% in veterans. This …
moderate cognitive impairment and with a prevalence rate of up to 22% in veterans. This …