[HTML][HTML] Novel advances in inhibiting advanced glycation end product formation using natural compounds

Q Song, J Liu, L Dong, X Wang, X Zhang - Biomedicine & Pharmacotherapy, 2021 - Elsevier
Advanced glycation end products (AGEs) are a group of complex compounds generated by
nonenzymatic interactions between proteins and reducing sugars or lipids. AGEs …

Beneficial effects of cinnamon and its extracts in the management of cardiovascular diseases and diabetes

C Shang, H Lin, X Fang, Y Wang, Z Jiang, Y Qu… - Food & function, 2021 - pubs.rsc.org
Cardiovascular diseases (CVDs) and diabetes are the leading causes of death worldwide,
which underlines the urgent necessity to develop new pharmacotherapies. Cinnamon has …

[HTML][HTML] Nox4 as a novel therapeutic target for diabetic vascular complications

D Wang, J Li, G Luo, J Zhou, N Wang, S Wang, R Zhao… - Redox Biology, 2023 - Elsevier
Diabetic vascular complications can affect both microvascular and macrovascular. Diabetic
microvascular complications, such as diabetic nephropathy, diabetic retinopathy, diabetic …

[Retracted] The Therapeutic Roles of Cinnamaldehyde against Cardiovascular Diseases

L Lu, Y Xiong, J Zhou, G Wang, B Mi… - Oxidative Medicine and …, 2022 - Wiley Online Library
Evidence from epidemiological studies has demonstrated that the incidence and mortality of
cardiovascular diseases (CVDs) increase year by year, which pose a great threat on social …

Artemisinin attenuates type 2 diabetic cardiomyopathy in rats through modulation of AGE-RAGE/HMGB-1 signaling pathway

EAE Farrag, MO Hammad, SM Safwat, S Hamed… - Scientific Reports, 2023 - nature.com
Diabetes mellitus is a common metabolic disorder. About two-thirds of diabetic patients
develop diabetic cardiomyopathy (DCM), which becomes a challenging issue as it severely …

Chemopreventive and Therapeutic Efficacy of Cinnamomum zeylanicum L. Bark in Experimental Breast Carcinoma: Mechanistic In Vivo and In Vitro Analyses

P Kubatka, M Kello, K Kajo, M Samec, K Jasek… - Molecules, 2020 - mdpi.com
Comprehensive oncology research suggests an important role of phytochemicals or whole
plant foods in the modulation of signaling pathways associated with anticancer action. The …

Pathological mechanisms linking diabetes mellitus and Alzheimer's disease: The receptor for advanced glycation end products (RAGE)

Y Kong, F Wang, J Wang, C Liu, Y Zhou… - Frontiers in aging …, 2020 - frontiersin.org
Diabetes and Alzheimer's disease (AD) place a significant burden on health care systems in
the world and its aging populations. These diseases have long been regarded as separate …

The Synergistic Influence of Polyflavonoids from Citrus aurantifolia on Diabetes Treatment and Their Modulation of the PI3K/AKT/FOXO1 Signaling Pathways …

MA Hassan, GMA Elmageed, IG El-Qazaz… - Pharmaceutics, 2023 - mdpi.com
This study was aimed at probing the modulatory influence of polyflavonoids extracted from
Citrus aurantifolia, lemon peel extract (LPE-polyflavonoids), on attenuating diabetes mellitus …

[HTML][HTML] New insight into the role of isorhamnetin as a regulator of insulin signaling pathway in type 2 diabetes mellitus rat model: Molecular and computational …

M Matboli, M Saad, AH Hasanin, LA Saleh… - Biomedicine & …, 2021 - Elsevier
We intended to examine the molecular mechanism of action of isorhamnetin (IHN) to
regulate the pathway of insulin signaling. Molecular analysis, immunofluorescence, and …

Cinnamaldehyde Mitigates Atherosclerosis Induced by High‐Fat Diet via Modulation of Hyperlipidemia, Oxidative Stress, and Inflammation

BS Ismail, B Mahmoud… - Oxidative Medicine …, 2022 - Wiley Online Library
Atherosclerosis is a disease in which plaque builds up inside arteries. Cinnamaldehyde (Ci)
has many biological properties that include anti‐inflammatory and antioxidant activities …