Precision medicine in diabetes: a consensus report from the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)
The convergence of advances in medical science, human biology, data science, and
technology has enabled the generation of new insights into the phenotype known as …
technology has enabled the generation of new insights into the phenotype known as …
Global aetiology and epidemiology of type 2 diabetes mellitus and its complications
Globally, the number of people with diabetes mellitus has quadrupled in the past three
decades, and diabetes mellitus is the ninth major cause of death. About 1 in 11 adults …
decades, and diabetes mellitus is the ninth major cause of death. About 1 in 11 adults …
Personalised nutrition and health
Personalised nutrition and health Page 1 the bmj | BMJ 2018;361:k2173 | doi: 10.1136/bmj.k2173
1 Science and PoliticS of nutrition Personalised nutrition and health Jose Ordovas and …
1 Science and PoliticS of nutrition Personalised nutrition and health Jose Ordovas and …
Associations of combined genetic and lifestyle risks with incident cardiovascular disease and diabetes in the UK Biobank Study
MA Said, N Verweij, P van der Harst - JAMA cardiology, 2018 - jamanetwork.com
Importance Genetic and lifestyle factors both contribute to the risk of developing
cardiovascular disease, but whether poor health behaviors are associated with similar …
cardiovascular disease, but whether poor health behaviors are associated with similar …
Developing and evaluating polygenic risk prediction models for stratified disease prevention
Abstract Knowledge of genetics and its implications for human health is rapidly evolving in
accordance with recent events, such as discoveries of large numbers of disease …
accordance with recent events, such as discoveries of large numbers of disease …
A novel diabetes typology: towards precision diabetology from pathogenesis to treatment
C Herder, M Roden - Diabetologia, 2022 - Springer
The current classification of diabetes, based on hyperglycaemia, islet-directed antibodies
and some insufficiently defined clinical features, does not reflect differences in aetiological …
and some insufficiently defined clinical features, does not reflect differences in aetiological …
Obesity, unfavourable lifestyle and genetic risk of type 2 diabetes: a case-cohort study
TM Schnurr, H Jakupović, GD Carrasquilla, L Ängquist… - Diabetologia, 2020 - Springer
Aims/hypothesis We aimed to investigate whether the impact of obesity and unfavourable
lifestyle on type 2 diabetes risk is accentuated by genetic predisposition. Methods We …
lifestyle on type 2 diabetes risk is accentuated by genetic predisposition. Methods We …
Genome-wide association analysis in humans links nucleotide metabolism to leukocyte telomere length
C Li, S Stoma, LA Lotta, S Warner, E Albrecht… - The American Journal of …, 2020 - cell.com
Leukocyte telomere length (LTL) is a heritable biomarker of genomic aging. In this study, we
perform a genome-wide meta-analysis of LTL by pooling densely genotyped and imputed …
perform a genome-wide meta-analysis of LTL by pooling densely genotyped and imputed …
Exposing the exposures responsible for type 2 diabetes and obesity
PW Franks, MI McCarthy - Science, 2016 - science.org
The rising prevalences of type 2 diabetes and obesity constitute major threats to human
health globally. Powerful social and economic factors influence the distribution of these …
health globally. Powerful social and economic factors influence the distribution of these …
Precision nutrition for prevention and management of type 2 diabetes
Precision nutrition aims to prevent and manage chronic diseases by tailoring dietary
interventions or recommendations to one or a combination of an individual's genetic …
interventions or recommendations to one or a combination of an individual's genetic …