Amyotrophic lateral sclerosis is a progressive adult-onset neurodegenerative disease that
primarily affects upper and lower motor neurons, but also frontotemporal and other regions …

Amyotrophic lateral sclerosis (ALS), also known as motor neuron disease, is characterized
by the degeneration of both upper and lower motor neurons, which leads to muscle …

Background Amyotrophic lateral sclerosis (ALS) is a relentlessly progressive, fatal motor
neuron disease with a variable natural history. There are no accurate models that predict the …

Bulbar impairment represents a hallmark feature of Amyotrophic Lateral Sclerosis (ALS) that
significantly impacts survival and quality of life. Speech and swallowing dysfunction are key …

Amyotrophic lateral sclerosis (ALS) is a progressive neuromuscular disease, with large
variation in survival between patients. Currently, it remains rather difficult to predict survival …

Background The survival time of amyotrophic lateral sclerosis (ALS) is greatly variable and
protective or risk effects of the potential survival predictors are controversial. Thus, we aim to …

Over the past 20 years, there has been a drastically increased understanding of the genetic
basis of Amyotrophic Lateral Sclerosis. Despite the identification of more than 40 different …

Introduction ALS functional rating scale (revised)(ALSFRS-R) is the most widely used
functional rating system in patients with amyotrophic lateral sclerosis (ALS). However …

Background: Amyotrophic Lateral Sclerosis (ALS) is a relentlessly progressive
neurodegenerative condition with limited therapeutic options at present. Survival from …

Amyotrophic lateral sclerosis (ALS) is a relentless neurodegenerative disease of the human
motor neuron system, where variability in progression rate limits clinical trial efficacy …