Microtubule-associated protein tau is abnormally aggregated in neuronal and glial cells in a
range of neurodegenerative diseases that are collectively referred to as tauopathies …

Annona muricata is a member of the Annonaceae family and is a fruit tree with a long history
of traditional use. A. muricata, also known as soursop, graviola and guanabana, is an …

Nueva edición del texto de referencia en farmacología que, con una trayectoria de más de
25 años se convierte en la obra de primera elección para el estudiante de Medicina, por su …

Tauopathies are classified according to whether tau deposits predominantly contain tau
isoforms with three or four repeats of the microtubule-binding domain. Those in which four …

Neurons are critically dependent on mitochondrial integrity based on specific morphological,
biochemical, and physiological features. They are characterized by high rates of metabolic …

Tau is a microtubule-associated protein with versatile functions in the dynamic assembly of
the neuronal cytoskeleton. Four-repeat (4R-) tauopathies are a group of neurodegenerative …

Research into the pathogenesis of Parkinson's disease has been rapidly advanced by the
development of animal models. Initial models were developed by using toxins that …

Degeneration of the dopamine (DA) neurons of the substantia nigra pars compacta and the
resulting loss of nerve terminals accompanied by DA deficiency in the striatum are …

Phytochemical complexity of plant extracts may offer health-promoting benefits including
chemotherapeutic and chemopreventive effects. Isolation of 'most-active fraction'or single …

Tropical fruits trade is on the rise due to the claimed health benefits related with their
consumption. Functional activities are exerted by the presence of bioactive compounds …