Comorbidities and the impact of atopic dermatitis

JI Silverberg - Annals of Allergy, Asthma & Immunology, 2019 - Elsevier
Objective Atopic dermatitis (AD) is a chronic pruritic inflammatory skin disease with
substantial patient and population burdens. A number of comorbid health problems occur in …

Personalized medicine—concepts, technologies, and applications in inflammatory skin diseases

T Litman - Apmis, 2019 - Wiley Online Library
The current state, tools, and applications of personalized medicine with special emphasis on
inflammatory skin diseases like psoriasis and atopic dermatitis are discussed. Inflammatory …

What are the best endpoints for Eczema Area and Severity Index and Scoring Atopic Dermatitis in clinical practice? A prospective observational study

JI Silverberg, D Lei, M Yousaf… - British Journal of …, 2021 - academic.oup.com
Background Multiple strategies have been used to evaluate the minimal important change
(MIC) of the Eczema Area and Severity Index (EASI) and Scoring Atopic Dermatitis …

Association of atopic dermatitis severity with cognitive function in adults

JI Silverberg, D Lei, M Yousaf, SR Janmohamed… - Journal of the American …, 2020 - Elsevier
Background Atopic dermatitis (AD) is associated with itch, pain, and sleep disturbance, all of
which may contribute toward cognitive dysfunction. Objective To determine the relationship …

An anti-OX40 antibody to treat moderate-to-severe atopic dermatitis: a multicentre, double-blind, placebo-controlled phase 2b study

E Guttman-Yassky, EL Simpson, K Reich, K Kabashima… - The Lancet, 2023 - thelancet.com
Background OX40 is crucial for T-cell differentiation and memory induction. The anti-OX40
antibody, rocatinlimab inhibits the OX40 pathway. We evaluated the efficacy and safety of …

Clinical phenotyping of atopic dermatitis using combined itch and lesional severity: a prospective observational study

R Chovatiya, D Lei, A Ahmed, R Chavda… - Annals of Allergy …, 2021 - Elsevier
Background Patients with atopic dermatitis (AD) have heterogeneous clinical phenotypes,
including different combinations of itch and lesional severity. Little is known about the …

Epidemiology and burden of sleep disturbances in atopic dermatitis in US adults

JI Silverberg, Z Chiesa-Fuxench, D Margolis… - Dermatitis, 2022 - liebertpub.com
Background The relationship between atopic dermatitis (AD) severity, sleep disturbance
(SD), and health-related outcomes is not fully elucidated. Objective The aim of the study was …

The impact of prurigo nodularis on quality of life: a systematic review and meta-analysis

SR Janmohamed, EC Gwillim, M Yousaf… - Archives of …, 2021 - Springer
Prurigo nodularis (PN) is a chronic, pruritic, debilitating disease. Previous studies found that
chronic pruritus in general negatively affects patients' quality of life (QoL). However, results …

Measuring atopic eczema symptoms in clinical practice: the first consensus statement from the Harmonising Outcome Measures for Eczema in clinical practice …

YA Leshem, JR Chalmers, C Apfelbacher… - Journal of the American …, 2020 - Elsevier
Background Measuring patient-centered outcomes in clinical practice is valuable for
monitoring patients and advancing real-world research. A new initiative from the …

[HTML][HTML] Patient-reported outcome (PRO) instruments for disease severity and quality of life in patients with atopic dermatitis: a systematic review of English and …

A Li, M Zhang, Y Yang, J Zhang, X Xie… - Annals of translational …, 2022 - ncbi.nlm.nih.gov
Background Many patient-reported outcome (PRO) on disease severity quality of life (QOL)
have been developed for atopic dermatitis (AD) patients. However, none of them on the …