Major review: Molecular genetics of primary open-angle glaucoma

Y Liu, RR Allingham - Experimental eye research, 2017 - Elsevier
Glaucoma is a leading cause of irreversible blindness worldwide. Primary open-angle
glaucoma (POAG), the most common type, is a complex inherited disorder that is …

The thick and thin of the central corneal thickness in glaucoma

GW Belovay, I Goldberg - Eye, 2018 - nature.com
Central corneal thickness (CCT) is an important parameter in the assessment of any
potential glaucoma patient. While it affects prognosis in ocular hypertension, its value in …

[HTML][HTML] Genetic associations for keratoconus: a systematic review and meta-analysis

SS Rong, STU Ma, XT Yu, L Ma, WK Chu, TCY Chan… - Scientific reports, 2017 - nature.com
Genetic associations for keratoconus could be useful for understanding disease
pathogenesis and discovering biomarkers for early detection of the disease. We conducted …

Central corneal thickness in glaucoma

CCA Sng, M Ang, K Barton - Current opinion in ophthalmology, 2017 - journals.lww.com
Central corneal thickness in glaucoma : Current Opinion in Ophthalmology Central corneal
thickness in glaucoma : Current Opinion in Ophthalmology Log in or Register Subscribe to …

[HTML][HTML] Mitophagy: an emerging target in ocular pathology

JM Skeie, DY Nishimura, CL Wang… - … & visual science, 2021 - iovs.arvojournals.org
Mitochondrial function is essential for the viability of aerobic eukaryotic cells, as
mitochondria provide energy through the generation of adenosine triphosphate (ATP) …

[HTML][HTML] Racial disparities in glaucoma: from epidemiology to pathophysiology

CJ Siegfried, YB Shui - Missouri Medicine, 2022 - ncbi.nlm.nih.gov
Among individuals of African and Latinx descent compared to those of European
background, there is a higher prevalence, earlier onset, more rapid progression of primary …

A comparative study of central corneal epithelial, stromal, and total thickness in males with and without primary open-angle glaucoma

H Batawi, IV Lollett, C Maliakal, SR Wellik… - Cornea, 2018 - journals.lww.com
Purpose: To compare the central corneal epithelial thickness (CET), stromal thickness
(CST), and total thickness (CCT) in males with and without primary open-angle glaucoma …

[HTML][HTML] Effects of vitrectomy and lensectomy on older rhesus macaques: oxygen distribution, antioxidant status, and aqueous humor dynamics

CJ Siegfried, YB Shui, B Tian, TM Nork… - … & visual science, 2017 - tvst.arvojournals.org
Purpose: The purpose of this study is to evaluate effects of vitrectomy (PPV) and lens
extraction with intraocular lens implantation (PE/IOL) on molecular oxygen (pO 2) …

Life under pressure: The role of ocular cribriform cells in preventing glaucoma

JS Paula, C O'Brien, WD Stamer - Experimental eye research, 2016 - Elsevier
Primary open-angle glaucoma is a multifactorial blinding disease often impacting the two
pressure-sensitive regions of the eye: the conventional outflow pathway and the optic nerve …

[HTML][HTML] Genetic variants in the FOXO1 and ZNF469 genes are associated with keratoconus in Sweden: a case-control study

W Wonneberger, B Sterner, U MacLean, M Claesson… - BMC …, 2024 - Springer
Background Keratoconus (KC) is characterized by pathological thinning and bulging of the
cornea that may lead to visual impairment. The etiology of sporadic KC remains enigmatic …