Adjuvant gonadotropin‐releasing hormone analogues for the prevention of chemotherapy‐induced premature ovarian failure in premenopausal women

H Chen, L Xiao, J Li, L Cui… - Cochrane Database of …, 2019 - cochranelibrary.com
Adjuvant gonadotropin‐releasing hormone analogues for the prevention of chemotherapy‐induced
premature ovarian failure in premenopausal women - Chen, H - 2019 | Cochrane Library Skip …

The impact of chemotherapy on the ovaries: molecular aspects and the prevention of ovarian damage

C Sonigo, I Beau, N Binart, M Grynberg - International journal of …, 2019 - mdpi.com
Cancer treatment, such as chemotherapy, induces early ovarian follicular depletion and
subsequent infertility. In order to protect gametes from the gonadotoxic effects of …

Melatonin mitigates cisplatin-induced ovarian dysfunction via altering steroidogenesis, inflammation, apoptosis, oxidative stress, and PTEN/PI3K/Akt/mTOR/AMPK …

A Al-Shahat, MAE Hulail, NMM Soliman, T Khamis… - Pharmaceutics, 2022 - mdpi.com
Ovarian damage and fertility impairment are major side effects of chemotherapy in pre-
menopausal cancer patients. Cisplatin is a widely used chemotherapeutic drug. The present …

[PDF][PDF] Ovarian microenvironment: challenges and opportunities in protecting against chemotherapy-associated ovarian damage

Y Guo, L Xue, W Tang, J Xiong, D Chen… - Human …, 2024 - academic.oup.com
BACKGROUND Chemotherapy-associated ovarian damage (CAOD) is one of the most
feared short-and long-term side effects of anticancer treatment in premenopausal women …

Syringic acid alleviates cisplatin-induced ovarian injury through modulating endoplasmic reticulum stress, inflammation and Nrf2 pathway

EA Demir - Journal of Trace Elements in Medicine and Biology, 2024 - Elsevier
Background Reproductive toxicity is one of the most important side effects of cisplatin (CIS)
and leading to discontinuation of treatment. Syringic acid (SA) is a phenolic acid whose …

Fertility-enhancing effects of inositol & vitamin C on cisplatin induced ovarian and uterine toxicity in rats via suppressing oxidative stress and apoptosis

AH Moslehi, F Hoseinpour, A Saber, MA Taheri… - Food and Chemical …, 2023 - Elsevier
Cisplatin can lead to infertility due to its negative impact on the uterus and ovaries. This
study aimed to explore the effects of Inositol and vitamin C on cisplatin-induced infertility …

Evaluation of the therapeutic effects of arbutin on cisplatin‐induced ovarian toxicity in rats through endoplasmic reticulum stress and Nrf2 pathway

EA Demir, A Mentese, ZS Yilmaz, NT Alemdar… - Reproductive …, 2023 - Elsevier
Arbutin (ARB) is a glycosylated hydroquinone with potent antioxidant effects. Although
cisplatin (CP) is widely used in chemotherapy, its toxicity in healthy tissues, including …

Effect of lycopene on oxidative ovary-damage induced by cisplatin in rats.

N Kulhan, M Kulhan, CAN TÜRKLER… - General physiology …, 2019 - avesis.ebyu.edu.tr
The anti-cancer drugs, particularly those used in reproductive period, may cause several
complications such as ovarian insufficiency and infertility. The mechanism of action of …

Consequences of chemotherapeutic agents on primordial follicles and future clinical applications

SY Kim, GJ Cho, JS Davis - Obstetrics & Gynecology Science, 2019 - synapse.koreamed.org
The ovarian reserve is necessary for female fertility and endocrine health. Commonly used
cancer therapies diminish the ovarian reserve, thus, resulting in primary ovarian …

The therapeutic effect of silibinin against 5‐fluorouracil‐induced ovarian toxicity in rats

E Ayazoglu Demir, A Mentese, H Kucuk… - … of Biochemical and …, 2023 - Wiley Online Library
Fluorouracil (5‐FU) is a fluoropyrimidine group antineoplastic drug with antimetabolite
properties and ovotoxicity is one of the most important side effects. Silibinin (SLB) is a …