Encoding sound in the cochlea: from receptor potential to afferent discharge

MA Rutherford, H von Gersdorff… - The Journal of …, 2021 - Wiley Online Library
Ribbon‐class synapses in the ear achieve analog to digital transformation of a continuously
graded membrane potential to all‐or‐none spikes. In mammals, several auditory nerve …

Single-cell RNA-sequencing analysis of the developing mouse inner ear identifies molecular logic of auditory neuron diversification

C Petitpré, L Faure, P Uhl, P Fontanet, I Filova… - Nature …, 2022 - nature.com
Different types of spiral ganglion neurons (SGNs) are essential for auditory perception by
transmitting complex auditory information from hair cells (HCs) to the brain. Here, we use …

Relative contribution of proprioceptive and vestibular sensory systems to locomotion: opportunities for discovery in the age of molecular science

T Akay, AJ Murray - International Journal of Molecular Sciences, 2021 - mdpi.com
Locomotion is a fundamental animal behavior required for survival and has been the subject
of neuroscience research for centuries. In terrestrial mammals, the rhythmic and coordinated …

Experience-dependent flexibility in a molecularly diverse central-to-peripheral auditory feedback system

MM Frank, AA Sitko, K Suthakar, LT Cadenas, M Hunt… - Elife, 2023 - elifesciences.org
Brainstem olivocochlear neurons (OCNs) modulate the earliest stages of auditory
processing through feedback projections to the cochlea and have been shown to influence …

Noise-induced hearing loss in gerbil: round window assays of synapse loss

PWC Jeffers, J Bourien, A Diuba, JL Puel… - Frontiers in cellular …, 2021 - frontiersin.org
Previous work in animals with recovered hearing thresholds but permanent inner hair cell
synapse loss after noise have suggested initial vulnerability of low spontaneous rate (SR) …

Peristimulus time responses predict adaptation and spontaneous firing of auditory-nerve fibers: from rodents data to humans

A Huet, C Batrel, X Dubernard, JC Kleiber… - Journal of …, 2022 - Soc Neuroscience
Sound-level coding in the auditory nerve is achieved through the progressive recruitment of
auditory nerve fibers (ANFs) that differ in threshold of activation and in the stimulus level at …

The role of GABAB receptors in the subcortical pathways of the mammalian auditory system

R Tureček, A Melichar, M Králíková… - Frontiers in …, 2023 - frontiersin.org
GABAB receptors are G-protein coupled receptors for the inhibitory neurotransmitter GABA.
Functional GABAB receptors are formed as heteromers of GABAB1 and GABAB2 subunits …

Bridging the gap between presynaptic hair cell function and neural sound encoding

LMJ Tobón, T Moser - bioRxiv, 2022 - biorxiv.org
Neural diversity can expand the encoding capacity of a circuitry. A striking example of
diverse structure and function is presented by the afferent synapses between inner hair cells …