Pain medication plays an important role in the treatment of acute and chronic pain
conditions, but some drugs, opioids in particular, have been overprescribed or prescribed …

The use of deep learning (DL) for the analysis and diagnosis of biomedical and health care
problems has received unprecedented attention in the last decade. The technique has …

Sustained pain is a major characteristic of clinical pain disorders, but it is difficult to assess in
isolation from co-occurring cognitive and emotional features in patients. In this study, we …

Abstract Machine learning is a powerful tool for creating computational models relating brain
function to behavior, and its use is becoming widespread in neuroscience. However, these …

Chronic pain is an endemic problem involving both peripheral and brain pathophysiology.
Although biomarkers have revolutionized many areas of medicine, biomarkers for pain have …

Since noxious stimulation usually leads to the perception of pain, pain has traditionally been
considered sensory nociception. But its variability and sensitivity to a broad array of …

Chronic pain is a common and severely disabling disease whose treatment is often
unsatisfactory. Insights into the brain mechanisms of chronic pain promise to advance the …

Osteoarthritis (OA) manifests with chronic pain, motor impairment, and proprioceptive
changes. However, the role of the brain in the disease is largely unknown. Here, we studied …

Current pain assessment techniques based only on clinical evaluation and self-reports are
not objective and may lead to inadequate treatment. Having a functional biomarker will add …

Chronic pain has widespread, detrimental effects on the human nervous system and its
prevalence and burden increase with age. Machine learning techniques have been applied …