The Kelch13 compartment contains highly divergent vesicle trafficking proteins in malaria parasites

S Schmidt, JS Wichers-Misterek, HM Behrens… - Plos …, 2023 - journals.plos.org
Single amino acid changes in the parasite protein Kelch13 (K13) result in reduced
susceptibility of P. falciparum parasites to artemisinin and its derivatives (ART). Recent work …

Putative prefoldin complex subunit 5 of Plasmodium berghei is crucial for microtubule formation and parasite development in the mosquito

R Beyeler, M Jordan, L Dorner, B He… - Molecular …, 2024 - Wiley Online Library
Plasmodium sporozoite development in and egress from oocysts in the Anopheles mosquito
remains largely enigmatic. In a previously performed high‐throughput knockout screen, the …

The novel Plasmodium berghei protein S14 is essential for sporozoite gliding motility and infectivity

A Ghosh, A Varshney, SK Narwal… - Journal of Cell …, 2024 - journals.biologists.com
Plasmodium sporozoites are the infective forms of the malaria parasite in the mosquito and
vertebrate host. Gliding motility allows sporozoites to migrate and invade mosquito salivary …

Plasmodium microtubule-binding protein EB1 is critical for partitioning of nuclei in male gametogenesis

S Mauer, N Camargo, BA Abatiyow, OR Gargaro… - Mbio, 2023 - Am Soc Microbiol
Sexual reproduction of the malaria parasites is critical for their transmission to a mosquito
vector. Several signaling molecules, such as kinases and phosphatases, are known to …

The three Plasmodium falciparum Aurora-related kinases display distinct temporal and spatial associations with mitotic structures in asexual blood stage parasites …

M Wyss, BT Thommen, J Kofler, E Carrington… - Msphere, 2024 - journals.asm.org
Aurora kinases are crucial regulators of mitotic cell cycle progression in eukaryotes. The
protozoan malaria parasite Plasmodium falciparum replicates via schizogony, a specialized …

Roles of the tubulin-based cytoskeleton in the Toxoplasma gondii apical complex

AT i Puig, D Soldati-Favre - Trends in Parasitology, 2024 - cell.com
Microtubules (MTs) play a vital role as key components of the eukaryotic cytoskeleton. The
phylum Apicomplexa comprises eukaryotic unicellular parasitic organisms defined by the …