Prefrontal cortex provides both inhibitory and excitatory input to distributed neural circuits
required to support performance in diverse tasks. Neurological patients with prefrontal …

The motor system includes structures distributed widely through the CNS, and in this feature
article we present a scheme for how they might cooperate in the control of action. Distributed …

Corticothalamic neurons provide massive input to the thalamus. This top-down projection
may allow the cortex to regulate sensory processing by modulating the excitability of …

All neocortical areas receive inputs from and project back to the thalamus. It is often said that
the corticothalamic projections are organized in a way that reciprocates the spatial …

Although it is now generally accepted that the thalamus is more than a simple relay of
sensory signals to the cortex, we are just beginning to gain an understanding of how …

The human capacity for vibrotactile frequency discrimination has been compared directly for
glabrous and hairy skin regions by means of a two-alternative, forced-choice psychophysical …

To follow an ever-changing auditory scene, the auditory brain is continuously creating a
representation of the past to form expectations about the future. Unexpected events will …

Tooth loss and its replacement have significant functional and psychosocial consequences.
The removal of intra-dental and periodontal mechanoreception accompanying tooth loss …

Corticothalamic (CT) projections are∼ 10 times more numerous than thalamocortical
projections, yet their function in sensory processing is poorly understood. In particular, the …

An animal's survival may depend on detecting new events or objects in its environment, and
it is likely that the brain has evolved specific mechanisms to detect such changes. In sensory …