HLA class II‐associated genetic susceptibility in multiple sclerosis: a critical evaluation

O Olerup, J Hillert - Tissue antigens, 1991 - Wiley Online Library
Multiple sclerosis (MS) has, since the 1970s, been known to be associated with the HLA‐
Dw2 and‐DR2 specificities in Caucasian Europeans and North Americans. By the use of …

Nomenclature for factors of the HLA system, 1995

JG Bodmer, SGE Marsh, ED Albert, WF Bodmer… - Human Immunology, 1995 - Elsevier
The WHO Nomenclature Committee for factors of the HLA system met in Brighton in March
1995 at the joint meeting of the European Foundation for Immunogenetics and British …

HLA-DQβ gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus

JA Todd, JI Bell, HO McDevitt - Nature, 1987 - nature.com
Over half of the inherited predisposition to insulin-dependent diabetes mellitus maps to the
region of chromosome 6 that contains the highly polymorphic HLA class II genes which …

A molecular basis for MHC class II—associated autoimmunity

JA Todd, H Acha-Orbea, JI Bell, N Chao, Z Fronek… - Science, 1988 - science.org
Class II major histocompatibility (MHC) molecules have an immunoregulatory role. These
cell-surface glycoproteins present fragments of protein antigens (or peptides) to thymus …

Allelic sequence variation of the HLA-DQ loci: relationship to serology and to insulin-dependent diabetes susceptibility.

GT Horn, TL Bugawan, CM Long… - Proceedings of the …, 1988 - National Acad Sciences
Analysis of sequence variation in the polymorphic second exon of the major
histocompatibility complex genes HLA-DQ alpha and-DQ beta has revealed 8 allelic …

A Newly Characterized HLA DQβ Allele Associated with Pemphigus Vulgaris

AA Sinha, C Brautbar, F Szafer, A Friedmann, E Tzfoni… - Science, 1988 - science.org
The inheritance of particular alleles of major histocompatibility complex class II genes
increases the risk for various human autoimmune diseases; however, only a small …

Primarily chronic progressive and relapsing/remitting multiple sclerosis: two immunogenetically distinct disease entities.

O Olerup, J Hillert, S Fredrikson… - Proceedings of the …, 1989 - National Acad Sciences
HLA class II gene polymorphism was investigated in 100 patients with clinically definite
multiple sclerosis (MS) by restriction fragment length polymorphism analysis of Taq I …

Nomenclature for factors of the HLA system, 1989

JG Bodmer, SGE Marsh, P Parham, HA Erlich, E Albert… - Immunobiology, 1990 - Elsevier
The WHO Nomenclature Committee for factors of the HLA system met during the 7th
International Congress of Immunology in Berlin in August 1989 to consider additions to the …

Alleles at four HLA class II loci determined by oligonucleotide hybridization and their associations in five ethnic groups

MA Fernandez-Viña, X Gao, ME Moraes, JR Moraes… - Immunogenetics, 1991 - Springer
The use of polymerase chain reaction (PCR) and oligonucleotide hybridization offers a new
approach for the definition of HLA class II alleles. It has been possible to determine 43 …

Different amino acids at position 57 of the HLA-DQβ chain associated with susceptibility and resistance to IgA deficiency

O Olerup, CI Edvard Smith, L Hammarström - Nature, 1990 - nature.com
THE human leukocyte antigens (HLA) are implicated in the genetic susceptibility to a large
number of diseases. Some of the diseases associated with HLA class II are related to …