Blood tests are considered as standard clinical procedures to screen for markers of diseases
and health conditions. However, the complex cellular background (> 99.9% RBCs) and …

Platelets are chief cells in hemostasis. Apart from their hemostatic roles, platelets are major
inflammatory effector cells that can influence both innate and adaptive immune responses …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an emergent pathogen
responsible for the coronavirus disease 2019 (COVID-19). Since its emergence, the novel …

There is an urgent need to understand the pathogenesis of coronavirus disease 2019
(COVID-19). In particular, thrombotic complications in patients with COVID-19 are common …

The pathophysiology of COVID-19–associated thrombosis seems to be multifactorial. We
hypothesized that COVID-19 is accompanied by procoagulant platelets with subsequent …

Platelets are hematopoietic cells whose main function has for a long time been considered
to be the maintenance of vascular integrity. They have an essential role in the hemostatic …

Objective: Thrombocytopenia is associated with many viral infections suggesting virions
interact with and affect platelets. Consistently, viral particles are seen inside platelets, and …

Severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) infection can trigger
the adaptive and innate immune responses, leading to uncontrolled inflammatory reactions …

Besides mediating hemostatic functions, platelets are increasingly recognized as important
players of inflammation. Data from experiments in mice and men revealed various …

Neutrophils are important components of the innate immune system that mediate pathogen
defense by multiple processes including phagocytosis, release of proteolytic enzymes …