Immune response following traumatic spinal cord injury: Pathophysiology and therapies
RC Sterner, RM Sterner - Frontiers in immunology, 2023 - frontiersin.org
Traumatic spinal cord injury (SCI) is a devastating condition that is often associated with
significant loss of function and/or permanent disability. The pathophysiology of SCI is …
significant loss of function and/or permanent disability. The pathophysiology of SCI is …
Acute spinal cord injury: Pathophysiology and pharmacological intervention
Y Zhang, A Al Mamun, Y Yuan… - Molecular …, 2021 - spandidos-publications.com
Spinal cord injury (SCI) is one of the most debilitating of all the traumatic conditions that
afflict individuals. For a number of years, extensive studies have been conducted to clarify …
afflict individuals. For a number of years, extensive studies have been conducted to clarify …
The search for translational pain outcomes to refine analgesic development: Where did we come from and where are we going?
R González-Cano, Á Montilla-García… - Neuroscience & …, 2020 - Elsevier
Pain measures traditionally used in rodents record mere reflexes evoked by sensory stimuli;
the results thus may not fully reflect the human pain phenotype. Alterations in physical and …
the results thus may not fully reflect the human pain phenotype. Alterations in physical and …
Grimace scale, burrowing, and nest building for the assessment of post-surgical pain in mice and rats—A systematic review
K Aulehner, C Leenaars, V Buchecker… - Frontiers in Veterinary …, 2022 - frontiersin.org
Several studies suggested an informative value of behavioral and grimace scale parameters
for the detection of pain. However, the robustness and reliability of the parameters as well as …
for the detection of pain. However, the robustness and reliability of the parameters as well as …
[HTML][HTML] Established and emerging therapies in acute spinal cord injury
Acute spinal cord injury (SCI) is devastating for patients and their caretakers and has an
annual incidence of 20–50 per million people. Following initial assessment with appropriate …
annual incidence of 20–50 per million people. Following initial assessment with appropriate …
Refinement of the motorised laminectomy-assisted rat spinal cord injury model by analgesic treatment
H Vijayakumar Sreelatha, H Palekkodan… - Plos one, 2024 - journals.plos.org
Usage and reporting of analgesia in animal models of spinal cord injury (SCI) have been
sparse and requires proper attention. The majority of experimental SCI research uses rats as …
sparse and requires proper attention. The majority of experimental SCI research uses rats as …
A new anesthetic protocol to medullary nerve roots access in rats
DR Santos, RKC Teixeira, NP Araújo… - Acta Cirúrgica …, 2021 - SciELO Brasil
Purpose: To describe a new anesthetic protocol medullary and nerve roots access and in
Rattus norvegicus. Methods: Seventy female Wistar rats (n= 70) were used. The animals …
Rattus norvegicus. Methods: Seventy female Wistar rats (n= 70) were used. The animals …
Management strategies for spinal cord injury pain updated for the twenty-first century
E Shaw, M Saulino - Physical Medicine and Rehabilitation …, 2020 - pmr.theclinics.com
Traumatic spinal cord injury (SCI) often results in several life-altering impairments, including
paralysis, sensory loss, and neurogenic bowel/bladder dysfunction. Some of these SCI …
paralysis, sensory loss, and neurogenic bowel/bladder dysfunction. Some of these SCI …
[PDF][PDF] A Review of Pharmacological and Cell-based Therapies in Spinal Cord Injury
S Amanollahi, H Kazemi Mehrjerdi - Journal of Cell and Molecular …, 2023 - jcmr.um.ac.ir
Spinal cord injury (SCI) is a severe central nervous system trauma (CNS) that has two
primary and secondary phases. The initial phase, which is irreversible, causes nerve tissue …
primary and secondary phases. The initial phase, which is irreversible, causes nerve tissue …
[PDF][PDF] Evidenz-basierte Belastungseinschätzung bei Labornagern in der post-operativen Phase und bei kabel-gebundener Ableitung
K Aulehner - 2022 - edoc.ub.uni-muenchen.de
Die aktuelle weltweite pandemische Situation im Rahmen von COVID-19 (Coronavirus
Disease 2019) hat die Relevanz von Tierversuchen verdeutlicht. Besonders in der …
Disease 2019) hat die Relevanz von Tierversuchen verdeutlicht. Besonders in der …