Background The production of peroxide and superoxide is an inevitable consequence of
aerobic metabolism, and while these particular'reactive oxygen species'(ROSs) can exhibit a …

Of all the chemical elements, oxygen is the most vital to the human body. The brain is the
most sensitive organ to oxygen deprivation (hypoxia), which, over an extended period, can …

Animals exposed to brief periods of moderate hypoxia (8% to 10% oxygen for 3 hours) are
protected against cerebral and cardiac ischemia between 1 and 2 days later. This hypoxia …

Traumatic brain injury (TBI) is a leading cause of morbidity and mortality in young people in
industrialized countries. Although various anti‐inflammatory and antiapoptotic modalities …

purpose. Retinal ganglion cell (RGC) loss occurs in response to increased intraocular
pressure (IOP) and/or retinal ischemia in glaucoma and leads to impairment of vision. This …

Erythropoietin, a hemotopoietic growth factor, has brain protective actions. This study
investigated the mechanisms of Recombinant Human EPO (rhEPO)-induced brain …

Fifteen years of evidence have established that the cytokine erythropoietin offers promise as
a treatment for brain injury. In particular, neonatal brain injury may be reduced or prevented …

A large body of evidence indicates that the hormone erythropoietin (EPO) exerts beneficial
effects in the central nervous system (CNS). To date, EPO's effect has been assessed in …

Among the properties of lactoferrin (LF) are bactericidal, antianemic, immunomodulatory,
antitumour, antiphlogistic effects. Previously we demonstrated its capacity to stabilize in vivo …

The injured brain can be stimulated to amplify its intrinsic restorative processes to improve
neurological function. Thus, after stroke, both cell and pharmacological neurorestorative …