More than 400 million people worldwide are chronically infected by the hepatitis B virus. The
virus is responsible for more than 300000 cases of liver cancer every year and for similar …

Following development of liver cirrhosis in patients with chronic hepatitis B, liver disease
may continue to progress and decompensation or hepatocellular carcinoma (HCC) may …

The first human orthotopic liver transplantation (LT) in Europe was performed by Sir Roy
Calne in Cambridge in 1968 [1], only one year after the first successful human liver …

BACKGROUND & AIMS: The effect of entecavir (ETV) therapy on viral suppression and
hepatic function in hepatitis B virus (HBV) patients with decompensated cirrhosis has not …

Background/Aims: A large amount of new data on the treatment of chronic hepatitis B has
become available such that the 2003 consensus statement requires revision and update …

Liver transplantation is the only alternative for patients with end-stage liver disease. Viral
hepatitis B and C are among the most common causes of cirrhosis and hepatocellular …

In patients with compensated hepatitis B virus (HBV) cirrhosis, active viral replication
correlates significantly with the risk of hepatic flare, decompensation, and the development …

Background & Aims: Chronic hepatitis B is a leading cause of death worldwide. To identify
patients who might require urgent liver transplantation despite antiviral therapy, we …

Uncontrolled studies have suggested a beneficial effect of lamivudine in patients with
decompensated cirrhosis caused by replicating hepatitis B virus (HBV). We analyzed the …

The effect of lamivudine treatment on the outcome of patients with hepatitis B e antigen
(HBeAg)‐negative chronic hepatitis is unclear. In a retrospective multicenter study, we have …