Zebrafish: development of a vertebrate model organism

JR Meyers - Current Protocols Essential Laboratory …, 2018 - Wiley Online Library
Zebrafish (Danio rerio) are a small‐bodied tropical, freshwater fish species originally from
South Asia. The ease of care, year‐round prolific breeding, and transparent, external …

From Cajal to connectome and beyond

LW Swanson, JW Lichtman - Annual review of neuroscience, 2016 - annualreviews.org
One goal of systems neuroscience is a structure-function model of nervous system
organization that would allow mechanistic linking of mind, brain, and behavior. A necessary …

Cre recombinase and other tyrosine recombinases

G Meinke, A Bohm, J Hauber, MT Pisabarro… - Chemical …, 2016 - ACS Publications
Tyrosine-type site-specific recombinases (T-SSRs) have opened new avenues for the
predictable modification of genomes as they enable precise genome editing in heterologous …

Automated neuronal reconstruction with super-multicolour Tetbow labelling and threshold-based clustering of colour hues

MN Leiwe, S Fujimoto, T Baba, D Moriyasu… - Nature …, 2024 - nature.com
Fluorescence imaging is widely used for the mesoscopic mapping of neuronal connectivity.
However, neurite reconstruction is challenging, especially when neurons are densely …

Multicolor strategies for investigating clonal expansion and tissue plasticity

L Dumas, S Clavreul, F Michon, K Loulier - Cellular and Molecular Life …, 2022 - Springer
Understanding the generation of complexity in living organisms requires the use of lineage
tracing tools at a multicellular scale. In this review, we describe the different multicolor …

Contemporary zebrafish transgenesis with Tol2 and application for Cre/lox recombination experiments

A Felker, C Mosimann - Methods in cell biology, 2016 - Elsevier
Spatiotemporal transgene regulation by transgenic DNA recombinases is a central tool for
reverse genetics in multicellular organisms, with excellent applications for misexpression …

Spectral reading of optical resonance-encoded cells in microfluidics

M Humar, A Upadhya, SH Yun - Lab on a Chip, 2017 - pubs.rsc.org
The ability to label individual cells is useful for single-cell-level studies of complex cellular
interactions and heterogeneity. Optically readable cell labeling is attractive as it can be …

The laminar organization of piriform cortex follows a selective developmental and migratory program established by cell lineage

E Martin-Lopez, K Ishiguro, CA Greer - Cerebral Cortex, 2019 - academic.oup.com
Piriform cortex (PC) is a 3-layer paleocortex receiving primary afferent input from the
olfactory bulb. The past decade has seen significant progress in understanding the synaptic …

Feedback between tissue packing and neurogenesis in the zebrafish neural tube

TW Hiscock, JB Miesfeld, KR Mosaliganti… - …, 2018 - journals.biologists.com
Balancing the rate of differentiation and proliferation in developing tissues is essential to
produce organs of robust size and composition. Although many molecular regulators have …

In vivo Functional Genomics for Undiagnosed Patients: The Impact of Small GTPases Signaling Dysregulation at Pan-Embryo Developmental Scale

A Lauri, G Fasano, M Venditti, B Dallapiccola… - Frontiers in Cell and …, 2021 - frontiersin.org
While individually rare, disorders affecting development collectively represent a substantial
clinical, psychological, and socioeconomic burden to patients, families, and society. Insights …