Epigenetics regulates gene expression and has been confirmed to play a critical role in a
variety of metabolic diseases, such as diabetes, obesity, non-alcoholic fatty liver disease …

Osteoporosis is a common metabolic bone disease, influenced by genetic and
environmental factors, that increases bone fragility and fracture risk and, therefore, has a …

Circular RNA (circRNA) is a class of endogenous noncoding RNA (ncRNA), presenting as a
special covalent closed loop without a 5′ cap or 3′ tail, maintaining resistance to RNA …

Osteoporosis is a systemic metabolic disease, mainly characterized by reduced bone
mineral density and destruction of bone tissue microstructure. However, the molecular …

The identification of key regulatory factors that control osteoclastogenesis is important.
Accumulating evidence indicates that circular RNAs (circRNAs) are discrete functional …

Periodontitis is a chronic complex inflammatory disease associated with a destructive host
immune response to microbial dysbiosis, leading to irreversible loss of tooth-supporting …

Circular RNAs (circRNAs), a class of non-coding RNAs (ncRNAs), are highly stable and
ubiquitous molecules that exhibit tissue-specific expression. Accumulating evidence has …

Bone is a mechanosensitive organ that provides strength and support. Many bone cells,
various pathways, and signaling molecules coordinate bone metabolism and also determine …

Bone loss is prevalent in clinical pathological phenomena such as osteoporosis, which is
characterized by decreased osteoblast function and number, increased osteoclast activity …

Bone marrow-derived mesenchymal stem cells (BM-MSCs), the common progenitor cells of
adipocytes and osteoblasts, have been recognized as the key mediator during bone …