Cholangiocarcinoma

PJ Brindley, M Bachini, SI Ilyas, SA Khan… - Nature reviews Disease …, 2021 - nature.com
Cholangiocarcinoma (CCA) is a highly lethal adenocarcinoma of the hepatobiliary system,
which can be classified as intrahepatic, perihilar and distal. Each anatomic subtype has …

Updated epidemiology of gastrointestinal cancers in East Asia

J Huang, DE Lucero-Prisno III, L Zhang, W Xu… - Nature Reviews …, 2023 - nature.com
Globally, gastrointestinal cancers represent more than one-fourth of all cancer incidence
and one-third of cancer-related mortality. Although there has been much progress in …

Cholangiocarcinoma: Epidemiology and risk factors

SA Khan, S Tavolari, G Brandi - Liver International, 2019 - Wiley Online Library
Cholangiocarcinoma (CCA) is a heterogeneous disease arising from a complex interaction
between host‐specific genetic background and multiple risk factors. Globally, CCA …

The role of cancer-associated fibroblasts and fibrosis in liver cancer

S Affo, LX Yu, RF Schwabe - Annual Review of Pathology …, 2017 - annualreviews.org
Liver cancer is the second leading cause of cancer mortality worldwide, causing more than
700,000 deaths annually. Because of the wide landscape of genomic alterations and limited …

Global trends in intrahepatic and extrahepatic cholangiocarcinoma incidence from 1993 to 2012

AA Florio, J Ferlay, A Znaor, D Ruggieri, CS Alvarez… - Cancer, 2020 - Wiley Online Library
Background Intrahepatic cholangiocarcinomas (ICCs) and extrahepatic
cholangiocarcinomas (ECCs) are highly lethal bile duct tumors. Their incidence can be …

[HTML][HTML] Guidelines for the diagnosis and management of intrahepatic cholangiocarcinoma

J Bridgewater, PR Galle, SA Khan, JM Llovet… - Journal of …, 2014 - Elsevier
Cholangiocarcinoma (CCA) comprises a heterogeneous group of cancers with pathologic
features of biliary tract differentiation, and is presumed to arise from the intra-or extrahepatic …

Pathogenesis, diagnosis, and management of cholangiocarcinoma

SI Ilyas, GJ Gores - Gastroenterology, 2013 - Elsevier
Cholangiocarcinomas (CCAs) are hepatobiliary cancers with features of cholangiocyte
differentiation; they can be classified anatomically as intrahepatic CCA (iCCA), perihilar …

Global trends in incidence rates of primary adult liver cancers: a systematic review and meta-analysis

P Dasgupta, C Henshaw, DR Youlden, PJ Clark… - Frontiers in …, 2020 - frontiersin.org
Background: Primary liver cancer is a leading cause of cancer deaths worldwide. Global
burden varies, reflecting geographical distribution of viral hepatitis. Our objective was to …

Mutation profiling in cholangiocarcinoma: prognostic and therapeutic implications

CR Churi, R Shroff, Y Wang, A Rashid, HSC Kang… - PloS one, 2014 - journals.plos.org
Background Cholangiocarcinoma (CCA) is clinically heterogeneous; intra and extrahepatic
CCA have diverse clinical presentations. Next generation sequencing (NGS) technology …

[PDF][PDF] Risk factors for cholangiocarcinoma

GL Tyson, HB El‐Serag - Hepatology, 2011 - Wiley Online Library
Cholangiocarcinoma (CC) is the second most common primary hepatic malignancy after
hepatocellular cancer. CC accounts for approximately 10%‐25% of all hepatobiliary …