During pregnancy, the mother must adapt her body systems to support nutrient and oxygen
supply for growth of the baby in utero and during the subsequent lactation. These include …

Although much progress is being made in understanding the molecular pathways in the
placenta that are involved in the pathophysiology of pregnancy-related disorders, a …

Maternal cardiovascular changes during pregnancy include an expansion of plasma
volume, increased cardiac output, decreased peripheral resistance, and increased …

The peptide hormone relaxin regulates the essential maternal haemodynamic adaptations
in early pregnancy through direct actions on the renal and systemic vasculature. These …

Successful pregnancy and reproduction are dependent on adequate uterine blood flow,
placental perfusion, and vascular responsivity to fetal demands. The ability to support …

The primate corpus luteum is a transient endocrine gland that differentiates from the
ovulatory follicle midway through the ovarian (menstrual) cycle. Its formation and limited …

Relaxin is a potent vasodilator of small resistance arteries and modifies arterial compliance
in some systemic vascular beds, yet receptors for relaxin, such as RXFP1, have only been …

Proper vascular tone and blood pressure regulation during pregnancy are important for
immediate and long-term cardiovascular health of the mother and her offspring …

The hormone relaxin is a 6-kDa peptide with high structural similarity to insulin. It is primarily
produced by the corpus luteum during pregnancy but is also synthesized by other …

Background The current routine endometrial preparation protocol for women with polycystic
ovary syndrome (PCOS) is hormone replacement treatment (HRT). Letrozole is rarely used …