CRISPR-based diagnostics
MM Kaminski, OO Abudayyeh, JS Gootenberg… - Nature Biomedical …, 2021 - nature.com
The accurate and timely diagnosis of disease is a prerequisite for efficient therapeutic
intervention and epidemiological surveillance. Diagnostics based on the detection of nucleic …
intervention and epidemiological surveillance. Diagnostics based on the detection of nucleic …
[HTML][HTML] Review of COVID-19 testing and diagnostic methods
O Filchakova, D Dossym, A Ilyas, T Kuanysheva… - Talanta, 2022 - Elsevier
More than six billion tests for COVID-19 has been already performed in the world. The
testing for SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus-2) virus and …
testing for SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus-2) virus and …
Wearable materials with embedded synthetic biology sensors for biomolecule detection
PQ Nguyen, LR Soenksen, NM Donghia… - Nature …, 2021 - nature.com
Integrating synthetic biology into wearables could expand opportunities for noninvasive
monitoring of physiological status, disease states and exposure to pathogens or toxins …
monitoring of physiological status, disease states and exposure to pathogens or toxins …
Amplification-free CRISPR/Cas detection technology: challenges, strategies, and perspectives
Rapid and accurate molecular diagnosis is a prerequisite for precision medicine, food
safety, and environmental monitoring. The clustered regularly interspaced short palindromic …
safety, and environmental monitoring. The clustered regularly interspaced short palindromic …
Fast and sensitive detection of SARS-CoV-2 RNA using suboptimal protospacer adjacent motifs for Cas12a
S Lu, X Tong, Y Han, K Zhang, Y Zhang… - Nature biomedical …, 2022 - nature.com
CRISPR-based assays for the detection of nucleic acids are highly specific, yet they are not
fast, sensitive or easy to use. Here we report a one-step fluorescence assay for the detection …
fast, sensitive or easy to use. Here we report a one-step fluorescence assay for the detection …
Multiplexed CRISPR-based microfluidic platform for clinical testing of respiratory viruses and identification of SARS-CoV-2 variants
Abstract The coronavirus disease 2019 (COVID-19) pandemic has demonstrated a clear
need for high-throughput, multiplexed and sensitive assays for detecting severe acute …
need for high-throughput, multiplexed and sensitive assays for detecting severe acute …
Minimally instrumented SHERLOCK (miSHERLOCK) for CRISPR-based point-of-care diagnosis of SARS-CoV-2 and emerging variants
The COVID-19 pandemic highlights the need for diagnostics that can be rapidly adapted
and deployed in a variety of settings. Several SARS-CoV-2 variants have shown worrisome …
and deployed in a variety of settings. Several SARS-CoV-2 variants have shown worrisome …
Simplified Cas13-based assays for the fast identification of SARS-CoV-2 and its variants
J Arizti-Sanz, AD Bradley, YB Zhang… - Nature biomedical …, 2022 - nature.com
The widespread transmission and evolution of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) call for rapid nucleic acid diagnostics that are easy to use …
coronavirus 2 (SARS-CoV-2) call for rapid nucleic acid diagnostics that are easy to use …
Lateral flow test engineering and lessons learned from COVID-19
The acceptability and feasibility of large-scale testing with lateral flow tests (LFTs) for clinical
and public health purposes has been demonstrated during the COVID-19 pandemic. LFTs …
and public health purposes has been demonstrated during the COVID-19 pandemic. LFTs …
Advanced point‐of‐care testing technologies for human acute respiratory virus detection
The ever‐growing global threats to human life caused by the human acute respiratory virus
(RV) infections have cost billions of lives, created a significant economic burden, and …
(RV) infections have cost billions of lives, created a significant economic burden, and …