Lung neoplasms are the leading cause of death by cancer worldwide. Non-small cell lung
cancer (NSCLC) constitutes more than 80% of all lung malignancies and the majority of …

Earlier access to lung cancer specialist (LCS) care improves survival, highlighting the need
for streamlined patient referral. International guidelines recommend 14-day maximum time …

To overcome the resistance of nonsmall cell lung cancer (NSCLC) cells to cisplatin and
inhibit their metastasis, we proposed to develop a Cu (II) agent based on the specific residue …

The prognostic and diagnostic value of microRNA (miRNA) expression aberrations in lung
cancer has been studied intensely in recent years. However, due to the application of …

Core–shell type lipid–polymer hybrid nanoparticles (CSLPHNPs) have emerged as a
multifunctional drug delivery platform. The delivery system combines mechanical …

The integrated stress response (ISR) is an essential stress-support pathway increasingly
recognized as a determinant of tumorigenesis. Here we demonstrate that ISR is pivotal in …

Background Significant evidence has shown that the miRNA pathway is an important
component in the downstream signaling cascades of TGF-β1 pathway. Our previous study …

This research work aims to fabricate cetuximab (CTX) decorated cabazitaxel (CBZ) loaded
redox-sensitive D-alpha-tocopheryl-polyethyleneglycol-1000-succinate (TPGS-SS) …

Platinum-based chemotherapy is used for non-small cell lung cancer (NSCLC). However, it
has side effects and minimum efficacy against lung cancer metastasis. In this study, platinum …

Non-small-cell lung cancer (NSCLC) is a major cause for cancer-related deaths around the
globe, partially due to the frequent recurrence and metastasis. Leucine-rich-alpha2 …