Fatigue in CKD: epidemiology, pathophysiology, and treatment

LP Gregg, M Bossola, M Ostrosky-Frid… - Clinical journal of the …, 2021 - journals.lww.com
Fatigue is a commonly reported and debilitating symptom among patients with CKD, yet little
is known about its epidemiology, pathogenesis, and treatment. Various measurement tools …

Effect of aerobic exercise on dialysis-related symptoms in individuals undergoing maintenance hemodialysis: a systematic review and meta-analysis of clinical trials

N Hargrove, N El Tobgy, O Zhou, M Pinder… - Clinical Journal of the …, 2021 - journals.lww.com
Background Hemodialysis is associated with a high symptom burden that impairs health-
related quality of life and functional status. Effective symptom management is a priority for …

[HTML][HTML] International consensus definitions of clinical trial outcomes for kidney failure: 2020

A Levin, R Agarwal, WG Herrington, HL Heerspink… - Kidney international, 2020 - Elsevier
Kidney failure is an important outcome for patients, clinicians, researchers, healthcare
systems, payers, and regulators. However, no harmonized international consensus …

[HTML][HTML] Implementing core outcomes in kidney disease: report of the Standardized Outcomes in Nephrology (SONG) implementation workshop

A Tong, B Manns, AYM Wang, B Hemmelgarn… - Kidney international, 2018 - Elsevier
There are an estimated 14,000 randomized trials published in chronic kidney disease. The
most frequently reported outcomes are biochemical endpoints, rather than clinical and …

Fatigue in patients receiving maintenance hemodialysis: a review

M Bossola, SS Hedayati, ADH Brys… - American Journal of Kidney …, 2023 - Elsevier
Fatigue surrounding hemodialysis treatments is a common and often debilitating symptom
that impacts patients' quality of life. Intradialytic fatigue develops or worsens immediately …

Patient-centred clinical trial design

A Tong, N Scholes-Robertson, C Hawley… - Nature Reviews …, 2022 - nature.com
Patient involvement in clinical trial design can facilitate the recruitment and retention of
participants as well as potentially increase the uptake of the tested intervention and the …

Characterization of exhaustion disorder and identification of outcomes that matter to patients: Qualitative content analysis of a Swedish national online survey

E Lindsäter, F Svärdman, P Rosquist… - Stress and …, 2023 - Wiley Online Library
Fatigue is a common presenting problem in healthcare settings, often attributed to chronic
psychosocial stress. Understanding of fatigue and development of evidence‐based …

Validation of a core patient-reported outcome measure for fatigue in patients receiving hemodialysis: the SONG-HD fatigue instrument

A Ju, A Teixeira-Pinto, A Tong, AC Smith… - Clinical Journal of the …, 2020 - journals.lww.com
Results In total, 485 participants completed the study across the United Kingdom, Australia,
and Romania. Psychometric assessment demonstrated that Standardized Outcomes in …

Global policy barriers and enablers to exercise and physical activity in kidney care

PN Bennett, M Kohzuki, C Bohm, B Roshanravan… - Journal of Renal …, 2022 - Elsevier
Objective Impairment in physical function and physical performance leads to decreased
independence and health-related quality of life in people living with chronic kidney disease …

Fostering innovation in symptom management among hemodialysis patients: paths forward for insomnia, muscle cramps, and fatigue

JE Flythe, T Hilliard, E Lumby, G Castillo… - Clinical journal of the …, 2019 - journals.lww.com
Individuals receiving in-center maintenance hemodialysis bear a high burden of both
physical and mood symptoms. More than half of patients on hemodialysis report sleep …