Bringing MicroRNAs to light: methods for MicroRNA quantification and visualization in live cells

T Siddika, IU Heinemann - Frontiers in bioengineering and …, 2021 - frontiersin.org
MiRNAs are small non-coding RNAs that interact with their target mRNAs for
posttranscriptional gene regulation. Finely controlled miRNA biogenesis, target recognition …

Development of gamma-tocotrienol as a radiation medical countermeasure for the acute radiation syndrome: Current status and future perspectives

VK Singh, TM Seed - Expert Opinion on Investigational Drugs, 2023 - Taylor & Francis
Introduction The possibility of exposure to high doses of total-or partial-body ionizing
radiation at a high dose rate due to radiological/nuclear accidents or terrorist attacks is …

iDEP: an integrated web application for differential expression and pathway analysis of RNA-Seq data

SX Ge, EW Son, R Yao - BMC bioinformatics, 2018 - Springer
Background RNA-seq is widely used for transcriptomic profiling, but the bioinformatics
analysis of resultant data can be time-consuming and challenging, especially for biologists …

Lung transcriptome of nonhuman primates exposed to total-and partial-body irradiation

NN Vellichirammal, S Sethi, S Pandey, J Singh… - … Therapy-Nucleic Acids, 2022 - cell.com
The focus of radiation biodosimetry has changed recently, and a paradigm shift for using
molecular technologies of omic platforms in addition to cytogenetic techniques has been …

Effects of gamma-tocotrienol on intestinal injury in a GI-specific acute radiation syndrome model in nonhuman primate

S Garg, TK Garg, SY Wise, OO Fatanmi… - International journal of …, 2022 - mdpi.com
The gastrointestinal (GI) system is highly susceptible to irradiation. Currently, there is no
Food and Drug Administration (FDA)-approved medical countermeasures for GI radiation …

[HTML][HTML] Long and short non-coding RNA and radiation response: a review

JM May, M Bylicky, S Chopra, CN Coleman… - Translational …, 2021 - Elsevier
Once thought of as arising from “junk DNA,” non-coding RNAs (ncRNAs) have emerged as
key molecules in cellular processes and response to stress. From diseases such as cancer …

RNA N6-methyladenosine modification-based biomarkers for absorbed ionizing radiation dose estimation

H Chen, X Zhao, W Yang, Q Zhang, R Hao… - Nature …, 2023 - nature.com
Radiation triage and biological dosimetry are critical for the medical management of
massive potentially exposed individuals following radiological accidents. Here, we …

Effects of gamma-tocotrienol on partial-body irradiation-induced intestinal injury in a nonhuman primate model

S Garg, TK Garg, IR Miousse, SY Wise, OO Fatanmi… - Antioxidants, 2022 - mdpi.com
Exposure to high doses of radiation, accidental or therapeutic, often results in
gastrointestinal (GI) injury. To date, there are no therapies available to mitigate GI injury after …

DAMPs and radiation injury

S Yamaga, M Aziz, A Murao, M Brenner… - Frontiers in …, 2024 - frontiersin.org
The heightened risk of ionizing radiation exposure, stemming from radiation accidents and
potential acts of terrorism, has spurred growing interests in devising effective …

Gamma-tocotrienol, a radiation countermeasure, reverses proteomic changes in serum following total-body gamma irradiation in mice

E Rosen, OO Fatanmi, SY Wise, VA Rao, VK Singh - Scientific Reports, 2022 - nature.com
Radiological incidents or terrorist attacks would likely expose civilians and military
personnel to high doses of ionizing radiation, leading to the development of acute radiation …