Biological membranes
H Watson - Essays in biochemistry, 2015 - portlandpress.com
Biological membranes allow life as we know it to exist. They form cells and enable
separation between the inside and outside of an organism, controlling by means of their …
separation between the inside and outside of an organism, controlling by means of their …
[HTML][HTML] Viroporins: structure and biological functions
JL Nieva, V Madan, L Carrasco - Nature Reviews Microbiology, 2012 - nature.com
Viroporins are small, hydrophobic proteins that are encoded by a wide range of clinically
relevant animal viruses. When these proteins oligomerize in host cell membranes, they form …
relevant animal viruses. When these proteins oligomerize in host cell membranes, they form …
[HTML][HTML] PEDV ORF3 encodes an ion channel protein and regulates virus production
Several studies suggest that the open reading frame 3 (ORF3) gene of porcine epidemic
diarrhea virus (PEDV) is related to viral infectivity and pathogenicity, but its function remains …
diarrhea virus (PEDV) is related to viral infectivity and pathogenicity, but its function remains …
Emodin inhibits current through SARS-associated coronavirus 3a protein
S Schwarz, K Wang, W Yu, B Sun, W Schwarz - Antiviral research, 2011 - Elsevier
The open-reading-frame 3a of SARS coronavirus (SARS-CoV) had been demonstrated
previously to form a cation-selective channel that may become expressed in the infected cell …
previously to form a cation-selective channel that may become expressed in the infected cell …
[HTML][HTML] Viral rhodopsins 1 are an unique family of light-gated cation channels
Phytoplankton is the base of the marine food chain as well as oxygen and carbon cycles and
thus plays a global role in climate and ecology. Nucleocytoplasmic Large DNA Viruses that …
thus plays a global role in climate and ecology. Nucleocytoplasmic Large DNA Viruses that …
Put a cork in it: Plugging the M2 viral ion channel to sink influenza
The ongoing threat of seasonal and pandemic influenza to human health requires antivirals
that can effectively supplement existing vaccination strategies. The M2 protein of influenza A …
that can effectively supplement existing vaccination strategies. The M2 protein of influenza A …
[HTML][HTML] Vpu protein: The viroporin encoded by HIV-1
ME González - Viruses, 2015 - mdpi.com
Viral protein U (Vpu) is a lentiviral viroporin encoded by human immunodeficiency virus type
1 (HIV-1) and some simian immunodeficiency virus (SIV) strains. This small protein of 81 …
1 (HIV-1) and some simian immunodeficiency virus (SIV) strains. This small protein of 81 …
[HTML][HTML] The ORF4a protein of human coronavirus 229E functions as a viroporin that regulates viral production
In addition to a set of canonical genes, coronaviruses encode additional accessory proteins.
A locus located between the spike and envelope genes is conserved in all coronaviruses …
A locus located between the spike and envelope genes is conserved in all coronaviruses …
[HTML][HTML] The p7 protein of hepatitis C virus forms structurally plastic, minimalist ion channels
DE Chandler, F Penin, K Schulten, C Chipot - 2012 - journals.plos.org
Hepatitis C virus (HCV) p7 is a membrane-associated oligomeric protein harboring ion
channel activity. It is essential for effective assembly and release of infectious HCV particles …
channel activity. It is essential for effective assembly and release of infectious HCV particles …
Insights into the oligomeric structure of the HIV-1 Vpu protein
The HIV-1-encoded protein Vpu forms an oligomeric ion channel/pore in membranes and
interacts with host proteins to support the virus lifecycle. However, Vpu molecular …
interacts with host proteins to support the virus lifecycle. However, Vpu molecular …