Proteins adopt different higher-order structures (HOS) to enable their unique biological
functions. Understanding the complexities of protein higher-order structures and dynamics …

Rapidly growing demand of functional polymers in various interdisciplinary areas of
research has accentuated the need for modern synthetic tools to develop advanced …

A two-step zero-length crosslinking procedure for studying protein-protein complexes has
been developed. One component of a complex is briefly incubated with 1-ethyl-3-(3 …

Water-soluble carbodiimides are frequently employed in coupling or conjugation reactions,
eg, to link a peptide immunogen to a carrier protein. However, their utility is limited by low …

Diagnosis and monitoring of complex diseases such as cancer require quantitative detection
of multiple proteins. Recent work has shown that when specific biomolecular binding occurs …

Modification of proteins, DNA, and other biopolymers by labeling them with reporter
molecules has become a very powerful research tool in immunology, histochem-istry, and …

Transforming growth factor fl (TGFB) signals through a heteromeric protein kinase receptor
that has a limited ability to bind ligand. This limitation is overcome by the action of …

Quantum dots are a group of inorganic nanomaterials exhibiting exceptional optical and
electronic properties which impart distinct advantages over traditional fluorescent organic …

Complementary bioconjugates based on antibody− antigen interactions were synthesized
from luminescent CdTe nanoparticles (NPs). Antigen (bovine serum albumin) was …

DC-SIGN and DC-SIGNR are cell-surface receptors that mediate cell-cell interactions within
the immune system by binding to intercellular adhesion molecule-3. The receptor …