Anaplastic thyroid carcinoma (ATC) is a rare malignancy, accounting for 1–2% of all thyroid
cancers. Although rare, ATC accounts for the majority of deaths from thyroid carcinoma. ATC …

Thyroid cancer is a common endocrine malignancy. There has been exciting progress in
understanding its molecular pathogenesis in recent years, as best exemplified by the …

Background: Anaplastic thyroid cancer (ATC) is a rare but highly lethal form of thyroid
cancer. Since the guidelines for the management of ATC by the American Thyroid …

BACKGROUND. Poorly differentiated thyroid cancer (PDTC) and anaplastic thyroid cancer
(ATC) are rare and frequently lethal tumors that so far have not been subjected to …

Thyroid cancer is a common type of endocrine malignancy, and its incidence has been
steadily increasing in many regions of the world. Initiation and progression of thyroid cancer …

Objectives: Next-generation sequencing (NGS) allows for high-throughput sequencing
analysis of large regions of the human genome. We explored the use of targeted NGS for …

Background The development of systemic treatment options leveraging the molecular
landscape of advanced thyroid cancer is a burgeoning field. This is a multidisciplinary …

PTEN/PI3K/AKT constitutes an important pathway regulating the signaling of multiple
biological processes such as apoptosis, metabolism, cell proliferation and cell growth. PTEN …

In recent years, the T1799A B-type Raf kinase (BRAF) mutation in thyroid cancer has
received enthusiastic investigation, and significant progress has been made toward …

Background: Anaplastic thyroid carcinomas (ATCs) are among the most lethal malignancies,
for which there is no effective treatment. Objective: In the present study, we aimed to …