A review of sorting, separation and isolation of cells and microbeads for biomedical applications: microfluidic approaches

A Dalili, E Samiei, M Hoorfar - Analyst, 2019 - pubs.rsc.org
Several biomedical analyses are performed on particular types of cells present in body
samples or using functionalized microparticles. Success in such analyses depends on the …

Liquid biopsy in prostate cancer management—Current challenges and future perspectives

F Crocetto, G Russo, E Di Zazzo, P Pisapia, BF Mirto… - Cancers, 2022 - mdpi.com
Simple Summary Prostate cancer (PCa) is a widespread malignancy, representing the
second leading cause of cancer-related death in men. In the last years, liquid biopsy has …

3D printing of inertial microfluidic devices

S Razavi Bazaz, O Rouhi, MA Raoufi, F Ejeian… - Scientific reports, 2020 - nature.com
Inertial microfluidics has been broadly investigated, resulting in the development of various
applications, mainly for particle or cell separation. Lateral migrations of these particles within …

Microfluidic‐based approaches in targeted cell/particle separation based on physical properties: fundamentals and applications

R Nasiri, A Shamloo, S Ahadian, L Amirifar, J Akbari… - Small, 2020 - Wiley Online Library
Cell separation is a key step in many biomedical research areas including biotechnology,
cancer research, regenerative medicine, and drug discovery. While conventional cell sorting …

Progress of inertial microfluidics in principle and application

Y Gou, Y Jia, P Wang, C Sun - Sensors, 2018 - mdpi.com
Inertial microfluidics has become a popular topic in microfluidics research for its good
performance in particle manipulation and its advantages of simple structure, high …

Recent advances in microfluidic platforms applied in cancer metastasis: Circulating tumor cells'(CTCs) isolation and tumor‐on‐a‐chip

Z Lin, G Luo, W Du, T Kong, C Liu, Z Liu - Small, 2020 - Wiley Online Library
Cancer remains the leading cause of death worldwide despite the enormous efforts that are
made in the development of cancer biology and anticancer therapeutic treatment …

The prognostic role of circulating tumor cells (CTCs) in lung cancer

J Kapeleris, A Kulasinghe, ME Warkiani, I Vela… - Frontiers in …, 2018 - frontiersin.org
Lung cancer affects over 1. 8 million people worldwide and is the leading cause of cancer
related mortality globally. Currently, diagnosis of lung cancer involves a combination of …

Rapid softlithography using 3D‐printed molds

S Razavi Bazaz, N Kashaninejad… - Advanced materials …, 2019 - Wiley Online Library
Polydimethylsiloxane (PDMS) is a long‐standing material of significant interest in
microfluidics due to its unique features. As such, rapid prototyping of PDMS‐based …

Microfluidics for label-free sorting of rare circulating tumor cells

S Zhu, F Jiang, Y Han, N Xiang, Z Ni - Analyst, 2020 - pubs.rsc.org
Circulating tumor cells (CTCs) have been widely considered as promising novel biomarkers
for molecular research and clinical diagnosis of cancer. However, the sorting of CTCs is very …

The prognostic significance of circulating tumor cells in head and neck and non‐small‐cell lung cancer

A Kulasinghe, J Kapeleris, R Kimberley… - Cancer …, 2018 - Wiley Online Library
Tumor biopsy is the gold standard for the assessment of clinical biomarkers for treatment.
However, tumors change dynamically in response to therapy, and there remains a need for …