The functional roles of the circRNA/Wnt axis in cancer

C Xue, G Li, Q Zheng, X Gu, Z Bao, J Lu, L Li - Molecular Cancer, 2022 - Springer
CircRNAs, covalently closed noncoding RNAs, are widely expressed in a wide range of
species ranging from viruses to plants to mammals. CircRNAs were enriched in the Wnt …

A comprehensive review of cancer MicroRNA therapeutic delivery strategies

A Forterre, H Komuro, S Aminova, M Harada - Cancers, 2020 - mdpi.com
In the field of molecular oncology, microRNAs (miRNAs) and their role in regulating
physiological processes and cancer pathogenesis have been a revolutionary discovery over …

Cobomarsen, an Oligonucleotide Inhibitor of miR-155, Slows DLBCL Tumor Cell Growth In Vitro and In Vivo

E Anastasiadou, AG Seto, X Beatty, M Hermreck… - Clinical Cancer …, 2021 - AACR
Purpose: miRNA-155 is an oncogenic miRNA highly expressed in B-cell malignancies,
particularly in the non–germinal center B-cell or activated B-cell subtype of diffuse large B …

Regulatory mechanisms of epigenetic miRNA relationships in human cancer and potential as therapeutic targets

KMT Arif, EK Elliott, LM Haupt, LR Griffiths - Cancers, 2020 - mdpi.com
Simple Summary By the virtue of targeting multiple genes, a microRNA (miRNA) can infer
variable consequences on tumorigenesis by appearing as both a tumour suppressor and …

miR‐155 as a biomarker in B‐cell malignancies

H Due, P Svendsen, JS Bødker… - BioMed research …, 2016 - Wiley Online Library
MicroRNAs have the potential to be useful biomarkers in the development of individualized
treatment since they are easy to detect, are relatively stable during sample handling, and are …

Comprehensive miRNA sequence analysis reveals survival differences in diffuse large B-cell lymphoma patients

EL Lim, DL Trinh, DW Scott, A Chu, M Krzywinski… - Genome biology, 2015 - Springer
Background Diffuse large B-cell lymphoma (DLBCL) is an aggressive disease, with 30% to
40% of patients failing to be cured with available primary therapy. microRNAs (miRNAs) are …

MicroRNA machinery genes as novel biomarkers for cancer

JT Huang, J Wang, V Srivastava, S Sen… - Frontiers in oncology, 2014 - frontiersin.org
MicroRNAs (miRNAs) directly and indirectly affect tumorigenesis. To be able to perform their
myriad roles, miRNA machinery genes, such as Drosha, DGCR8, Dicer1, XPO5, TRBP, and …

Plasma exosomal miR-223 expression regulates inflammatory responses during cardiac surgery with cardiopulmonary bypass

KS Poon, K Palanisamy, SS Chang, KT Sun… - Scientific reports, 2017 - nature.com
Cardiopulmonary bypass (CPB) induces inflammatory responses, and effective endogenous
homeostasis is important for preventing systemic inflammation. We assessed whether …

[HTML][HTML] Anti-malarial humoral immunity: the long and short of it

KJ Rogers, R Vijay, NS Butler - Microbes and infection, 2021 - Elsevier
Humoral immunity is critical for limiting Plasmodium parasite infections and the severity of
malaria. Naturally acquired immunity against malaria occurs inefficiently and protection is …

Systematic review of the potential of MicroRNAs in diffuse large B cell lymphoma

A Larrabeiti-Etxebarria, M Lopez-Santillan… - Cancers, 2019 - mdpi.com
Diffuse large B cell lymphoma (DLBCL) is the most common subtype of invasive non-
Hodgkin's lymphoma (NHL). DLBCL presents with variable backgrounds, which results in …