Is early-onset cancer an emerging global epidemic? Current evidence and future implications

T Ugai, N Sasamoto, HY Lee, M Ando… - Nature Reviews …, 2022 - nature.com
Over the past several decades, the incidence of early-onset cancers, often defined as
cancers diagnosed in adults< 50 years of age, in the breast, colorectum, endometrium …

Updated epidemiology of gastrointestinal cancers in East Asia

J Huang, DE Lucero-Prisno III, L Zhang, W Xu… - Nature Reviews …, 2023 - nature.com
Globally, gastrointestinal cancers represent more than one-fourth of all cancer incidence
and one-third of cancer-related mortality. Although there has been much progress in …

Diagnosis and management of Barrett's esophagus: an updated ACG guideline

NJ Shaheen, GW Falk, PG Iyer, RF Souza… - Official journal of the …, 2022 - journals.lww.com
Barrett's esophagus (BE) is a common condition associated with chronic gastroesophageal
reflux disease. BE is the only known precursor to esophageal adenocarcinoma, a highly …

Oesophageal cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up☆

R Obermannová, M Alsina, A Cervantes… - Annals of …, 2022 - annalsofoncology.org
Oesophageal cancer is the seventh most common cancer worldwide, with 604 000 new
cases diagnosed in 2020. It is the sixth most common cause of cancer-related mortality, with …

The microbiome and rise of early-onset cancers: knowledge gaps and research opportunities

K Mima, T Hamada, K Inamura, H Baba, T Ugai… - Gut …, 2023 - Taylor & Francis
Accumulating evidence indicates an alarming increase in the incidence of early-onset
cancers, which are diagnosed among adults under 50 years of age, in the colorectum …

Wide-area transepithelial sampling for dysplasia detection in Barrett's esophagus: a systematic review and meta-analysis

DC Codipilly, AK Chandar, KK Wang, DA Katzka… - Gastrointestinal …, 2022 - Elsevier
Background and Aims Seattle protocol forceps biopsy sampling (FB) is currently
recommended for surveillance in Barrett's esophagus (BE) but limited by sampling error and …

Cancer statistics for young adults aged 20 to 49 years in China from 2000 to 2017: a population-based registry study

Y Teng, C Xia, H Li, M Cao, F Yang, X Yan… - Science China Life …, 2024 - Springer
An increasing cancer incidence among adults younger than 50 years has been reported for
several types of cancer in multiple countries. We aimed to report cancer profiles and trends …

Gastrointestinal adenocarcinoma incidence and survival trends in South Australia, 1990–2017

D Schell, S Ullah, ME Brooke-Smith, P Hollington… - Cancers, 2022 - mdpi.com
Simple Summary This study from South Australia using the state's Cancer Registry data
provides compelling evidence for a significant increase in the incidence of young-onset (18 …

Proportion of early-onset gastric and esophagus cancers has changed over time with disproportionate impact on Black and Hispanic patients

NV Torrejon, S Deshpande, W Wei, K Tullio… - JCO Oncology …, 2022 - ascopubs.org
PURPOSE: The proportion of gastroesophageal junction adenocarcinoma is increasing.
This study evaluated trends in early-onset gastric and esophageal cancers and compared …

Surveillance in Barrett's esophagus: challenges, progress, and possibilities

PG Iyer, A Chak - Gastroenterology, 2023 - Elsevier
Endoscopic surveillance of Barrett's esophagus, aiming to detect prevalent dysplasia and
adenocarcinoma, followed by effective endoscopic treatment, is an integral part of the …