The explosion of clinical textual data has drawn the attention of researchers. Owing to the
abundance of clinical data, it is becoming difficult for healthcare professionals to take real …

Ovarian cancer (OC) is the 5th most common malignancy in women, and the leading cause
of death from gynecologic malignancies. Owing to tumor heterogeneity, lack of reliable early …

Epigenetic processes are radically altered in cancer cells. The altered epigenetic events
may include histone post-translational modifications (PTMs), DNA modifications, and/or …

Cancer cells display complex genomic aberrations that include large-scale genetic
rearrangements and epigenetic modulation that are not easily characterized by short-read …

Detecting potential locations of CpG islands is one of the first steps for predicting promoter
regions of many housekeeping and tissue-specific genes, which in turn, helps identify many …

摘要DNA 甲基化是基因表达调控的重要方式, 一般被认为以CpG 岛形式发挥作用;
近年的研究表明, 位点特异的DNA 甲基化以元件(cis-regulatory element) 的形式在生物微进化 …

Accurate detection of CpG islands plays a pivotal role in uncovering potential promoter
regions for housekeeping and tissue-specific genes, shedding light on critical epigenetic …

Abstract Properties of non‐canonical GC base pairs and their relations with
mechanochemical cleavage of DNA are analyzed. A hypothesis of the involvement of the …

RESUMO A síndrome mielodisplásica (SMD) é definida como um grupo heterogêneo de
doenças clonais das células progenitoras hematopoiéticas caracterizada por citopenias e …

В течение последних десяти лет работы в области ЯМР ДНК позволили
регистрировать не только канонические Уотсон-Криковские пары в ДНК, но и …