Pain-relief learning in flies, rats, and man: basic research and applied perspectives

B Gerber, A Yarali, S Diegelmann, CT Wotjak… - Learning & …, 2014 - learnmem.cshlp.org
Memories relating to a painful, negative event are adaptive and can be stored for a lifetime
to support preemptive avoidance, escape, or attack behavior. However, under unfavorable …

Molecular mechanisms underlying formation of long-term reward memories and extinction memories in the honeybee (Apis mellifera)

D Eisenhardt - Learning & memory, 2014 - learnmem.cshlp.org
The honeybee (Apis mellifera) has long served as an invertebrate model organism for
reward learning and memory research. Its capacity for learning and memory formation is …

Reinforcement signaling of punishment versus relief in fruit flies

C König, A Khalili, M Ganesan, AP Nishu… - Learning & …, 2018 - learnmem.cshlp.org
Painful events establish opponent memories: cues that precede pain are remembered
negatively, whereas cues that follow pain, thus coinciding with relief are recalled positively …

Optogenetically induced reward and 'frustration' memory in larval Drosophila melanogaster

J Thoener, A Weiglein, B Gerber… - Journal of …, 2022 - journals.biologists.com
Animals, including humans, form oppositely valenced memories for stimuli that predict the
occurrence versus the termination of a reward: appetitive 'reward'memory for stimuli …

Learning mechanisms underlying threat absence and threat relief: Influences of trait anxiety

M Andreatta, P Pauli - Neurobiology of Learning and Memory, 2017 - Elsevier
Impaired safety learning has been proposed as a risk factor for anxiety disorders, but safety
can be indicated by either threat absence or threat termination (ie, relief). Here, we …

Synapsin determines memory strength after punishment-and relief-learning

T Niewalda, B Michels, R Jungnickel… - Journal of …, 2015 - Soc Neuroscience
Adverse life events can induce two kinds of memory with opposite valence, dependent on
timing:“negative” memories for stimuli preceding them and “positive” memories for stimuli …

Developing valid behavioral indicators of animal pain

E Irvine - philosophical topics, 2020 - JSTOR
Identifying which nonhuman animal species are capable of feeling pain is important both for
understanding pain mechanisms more generally and for informing animal welfare …

[HTML][HTML] Aversive learning of colored lights in walking honeybees

NH Kirkerud, U Schlegel… - Frontiers in behavioral …, 2017 - frontiersin.org
The honeybee has been established as an important model organism in studies on visual
learning. So far the emphasis has been on appetitive conditioning, simulating floral …

How disappointing: Startle modulation reveals conditional stimuli presented after pleasant unconditional stimuli acquire negative valence

LJS Green, CC Luck, OV Lipp - Psychophysiology, 2020 - Wiley Online Library
Past research on backward conditioning in evaluative and fear conditioning yielded
inconsistent results in that self‐report measures suggest that the conditional stimulus (CS) …

Smell and Aftersmell: Fast Calcium Imaging Dynamics of Honey Bee Olfactory Coding

M Paoli, A Wystrach, B Ronsin, M Giurfa - bioRxiv, 2023 - biorxiv.org
Odour processing exhibits multiple parallels between vertebrate and invertebrate olfactory
systems. Insects, in particular, have emerged as relevant models for olfactory studies …