Mechanics of the brain: perspectives, challenges, and opportunities
A Goriely, MGD Geers, GA Holzapfel… - … and modeling in …, 2015 - Springer
The human brain is the continuous subject of extensive investigation aimed at
understanding its behavior and function. Despite a clear evidence that mechanical factors …
understanding its behavior and function. Despite a clear evidence that mechanical factors …
Use of brain biomechanical models for monitoring impact exposure in contact sports
Head acceleration measurement sensors are now widely deployed in the field to monitor
head kinematic exposure in contact sports. The wealth of impact kinematics data provides …
head kinematic exposure in contact sports. The wealth of impact kinematics data provides …
Brain stiffness increases with myelin content
Brain stiffness plays an important role in neuronal development and disease, but reported
stiffness values vary significantly for different species, for different brains, and even for …
stiffness values vary significantly for different species, for different brains, and even for …
An anatomically detailed and personalizable head injury model: Significance of brain and white matter tract morphological variability on strain
Finite element head (FE) models are important numerical tools to study head injuries and
develop protection systems. The generation of anatomically accurate and subject-specific …
develop protection systems. The generation of anatomically accurate and subject-specific …
Finite element methods in human head impact simulations: a review
A Madhukar, M Ostoja-Starzewski - Annals of biomedical engineering, 2019 - Springer
Head impacts leading to traumatic brain injury (TBI) present a major health risk today,
projected to become the third leading cause of death by 2020. While finite element (FE) …
projected to become the third leading cause of death by 2020. While finite element (FE) …
Embedded axonal fiber tracts improve finite element model predictions of traumatic brain injury
With the growing rate of traumatic brain injury (TBI), there is an increasing interest in
validated tools to predict and prevent brain injuries. Finite element models (FEM) are …
validated tools to predict and prevent brain injuries. Finite element models (FEM) are …
Lateral impacts correlate with falx cerebri displacement and corpus callosum trauma in sports-related concussions
Corpus callosum trauma has long been implicated in mild traumatic brain injury (mTBI), yet
the mechanism by which forces penetrate this structure is unknown. We investigated the …
the mechanism by which forces penetrate this structure is unknown. We investigated the …
A three-dimensional computational human head model that captures live human brain dynamics
Diffuse axonal injury (DAI) is a debilitating consequence of traumatic brain injury (TBI)
attributed to abnormal stretching of axons caused by blunt head trauma or acceleration of …
attributed to abnormal stretching of axons caused by blunt head trauma or acceleration of …
Volumetric MRI findings in mild traumatic brain injury (mTBI) and neuropsychological outcome
ED Bigler - Neuropsychology Review, 2023 - Springer
Region of interest (ROI) volumetric assessment has become a standard technique in
quantitative neuroimaging. ROI volume is thought to represent a coarse proxy for making …
quantitative neuroimaging. ROI volume is thought to represent a coarse proxy for making …
White matter tract-oriented deformation predicts traumatic axonal brain injury and reveals rotational direction-specific vulnerabilities
S Sullivan, SA Eucker, D Gabrieli, C Bradfield… - … and modeling in …, 2015 - Springer
A systematic correlation between finite element models (FEMs) and histopathology is
needed to define deformation thresholds associated with traumatic brain injury (TBI). In this …
needed to define deformation thresholds associated with traumatic brain injury (TBI). In this …