The human immune response is a complex process that responds to numerous exogenous
antigens in preventing infection by microorganisms, as well as to endogenous components …

Vγ9Vδ2-T cells are considered as potent effector cells for tumor immunotherapy through
directly killing tumor cells and indirectly regulating other innate and adaptive immune cells to …

Interactions between T cells and antigen-presenting cells (APCs) are the first step in the
induction of an adaptive immune response. Here, we show that CD6 and its ligand activated …

The T cell surface glycoprotein, CD6 binds CD166 in the first example of an interaction
between a scavenger receptor cysteine‐rich domain and an immunoglobulin‐like domain …

CD6 is a cell surface receptor expressed on immature thymocytes and mature T and B1a
lymphocytes. The ultimate function of CD6 has not been deciphered yet, but much evidence …

The CD6 glycoprotein is a lymphocyte surface receptor putatively involved in T cell
development and activation. CD6 facilitates adhesion between T cells and antigen …

The T lineage glycoprotein CD6 is generally considered to be a costimulator of T‐cell
activation. Here, we demonstrate that CD6 significantly reduces early and late T‐cell …

Deciphering the role of lymphocyte membrane proteins depends on dissecting the role of a
protein in the steady state and on engagement with its ligand. We show that expression of …

Following T cell receptor triggering, T cell activation is initiated and amplified by the
assembly at the TCR/CD3 macrocomplex of a multitude of stimulatory enzymes that activate …

Human Vγ9Vδ2 T cells, a major innate-like peripheral T cell subset, are thought to play in
vivo a key role in innate and adaptive immune responses to infection agents and tumors …