The future of cystic fibrosis care: a global perspective
Executive summary The past six decades have seen remarkable improvements in health
outcomes for people with cystic fibrosis, which was once a fatal disease of infants and young …
outcomes for people with cystic fibrosis, which was once a fatal disease of infants and young …
A guide to therapeutic drug monitoring of β‐lactam antibiotics
AJ Fratoni, DP Nicolau, JL Kuti - Pharmacotherapy: The Journal …, 2021 - Wiley Online Library
Therapeutic drug monitoring (TDM) opens the door to personalized medicine, yet it is
infrequently applied to β‐lactam antibiotics, one of the most commonly prescribed drug …
infrequently applied to β‐lactam antibiotics, one of the most commonly prescribed drug …
[HTML][HTML] Airway commensal bacteria in cystic fibrosis inhibit the growth of P. aeruginosa via a released metabolite
In cystic fibrosis (CF), Pseudomonas aeruginosa infection plays a critical role in disease
progression. Although multiple studies suggest that airway commensals might be able to …
progression. Although multiple studies suggest that airway commensals might be able to …
[HTML][HTML] International BEAT-PCD consensus statement for infection prevention and control for primary ciliary dyskinesia in collaboration with ERN-LUNG PCD Core …
JK Marthin, JS Lucas, M Boon, C Casaulta… - ERJ open …, 2021 - Eur Respiratory Soc
Introduction In primary ciliary dyskinesia (PCD) impaired mucociliary clearance leads to
recurrent airway infections and progressive lung destruction, and concern over chronic …
recurrent airway infections and progressive lung destruction, and concern over chronic …
Adapting the James Lind Alliance priority setting process to better support patient participation: an example from cystic fibrosis
NJ Rowbotham, SJ Smith, ZC Elliott… - Research Involvement …, 2019 - Springer
Plain English summary Cystic fibrosis (CF) is the commonest life-limiting inherited disorder
in the UK. It affects many parts of the body including the lungs and gut leading to increased …
in the UK. It affects many parts of the body including the lungs and gut leading to increased …
[HTML][HTML] Hope in every breath: navigating the therapeutic landscape of cystic fibrosis
H Sreenivasulu, S kumar Muppalla, S Vuppalapati… - Cureus, 2023 - ncbi.nlm.nih.gov
Cystic fibrosis (CF) has long posed a complex challenge to medical science. Still, the tides
are turning with remarkable progress in prognosis and demographics, thanks to cutting …
are turning with remarkable progress in prognosis and demographics, thanks to cutting …
[HTML][HTML] α-Tocopherol pharmacokinetics in adults with cystic fibrosis: benefits of supplemental vitamin C administration
Background: Numerous abnormalities in cystic fibrosis (CF) could influence tocopherol
absorption, transportation, storage, metabolism and excretion. We hypothesized that the …
absorption, transportation, storage, metabolism and excretion. We hypothesized that the …
The lancet respiratory medicine commission on the future of care of cystic fibrosis
The past six decades have seen remarkable improvements in health outcomes for people
with cystic fibrosis (CF), which was once a fatal disease of infants and young children …
with cystic fibrosis (CF), which was once a fatal disease of infants and young children …
Infection prevention and control in cystic fibrosis: One size fits all The argument against
AR Smyth, SJ Smith, NJ Rowbotham - Paediatric Respiratory Reviews, 2020 - Elsevier
As awareness of the risks of cross infection has increased, infection prevention and control
measures have become more draconian. Infection control measures can have a profound …
measures have become more draconian. Infection control measures can have a profound …
[HTML][HTML] Evaluating the alginate oligosaccharide (OligoG) as a therapy for Burkholderia cepacia complex cystic fibrosis lung infection
R Fischer, C Schwarz, R Weiser… - Journal of Cystic …, 2022 - Elsevier
OligoG has previously shown potentiation of aztreonam against Burkholderia cepacia
complex (Bcc) through biofilm disruption. A randomized, double-blind, placebo-controlled …
complex (Bcc) through biofilm disruption. A randomized, double-blind, placebo-controlled …