Cortical projection neurons polarize and form an axon while migrating radially. Even though
these dynamic processes are closely interwoven, they are regulated separately—the …

Gene expression is a fundamental process that regulates diverse biological activities across
all life stages. Given its vital role, there is an urgent need to develop innovative …

Neuritogenesis is crucial for establishing proper neuronal connections during brain
development; its failure causes neurodevelopmental defects. Cullin-RING E3 ubiquitin …

Abstract Development of the mammalian neocortex requires proper inside‐out migration of
developing cortical neurons from the germinal ventricular zone toward the cortical plate. The …

Axon-dendrite formation is a crucial milestone in the life history of neurons. During this
process, historically referred as “the establishment of polarity,” newborn neurons undergo …

Aging compromises brain function leading to cognitive decline. A cyclic ketogenic diet (KD)
improves memory in aged mice after long-term administration; however, short-term effects …

ATRX is a chromatin remodelling ATPase that is involved in transcriptional regulation, DNA
damage repair and heterochromatin maintenance. It has been widely studied for its role in …

RhoA plays a crucial role in neuronal polarization, where its action restraining axon
outgrowth has been thoroughly studied. We now report that RhoA has not only an inhibitory …

Autophagy is being involved in an increasing number of cellular pathways. It now appears
that autophagy stimulation and inhibition have complex effects in neurons. Here, we present …

Aging is a complex biological process that compromises brain function and neuronal
network activity, leading to cognitive decline and synaptic dysregulation. In recent years, a …