LNCcation: lncRNA localization and function
MC Bridges, AC Daulagala, A Kourtidis - Journal of Cell Biology, 2021 - rupress.org
Subcellular localization of RNAs has gained attention in recent years as a prevalent
phenomenon that influences numerous cellular processes. This is also evident for the large …
phenomenon that influences numerous cellular processes. This is also evident for the large …
P-bodies: composition, properties, and functions
Processing bodies (P-bodies) are cytoplasmic ribonucleoprotein (RNP) granules primarily
composed of translationally repressed mRNAs and proteins related to mRNA decay …
composed of translationally repressed mRNAs and proteins related to mRNA decay …
Towards a molecular understanding of microRNA-mediated gene silencing
S Jonas, E Izaurralde - Nature reviews genetics, 2015 - nature.com
MicroRNAs (miRNAs) are a conserved class of small non-coding RNAs that assemble with
Argonaute proteins into miRNA-induced silencing complexes (miRISCs) to direct post …
Argonaute proteins into miRNA-induced silencing complexes (miRISCs) to direct post …
Argonaute proteins: functional insights and emerging roles
G Meister - Nature Reviews Genetics, 2013 - nature.com
Small-RNA-guided gene regulation has emerged as one of the fundamental principles in
cell function, and the major protein players in this process are members of the Argonaute …
cell function, and the major protein players in this process are members of the Argonaute …
Endogenous RNAs modulate microRNA sorting to exosomes and transfer to acceptor cells
ML Squadrito, C Baer, F Burdet, C Maderna… - Cell reports, 2014 - cell.com
MicroRNA (miRNA) transfer via exosomes may mediate cell-to-cell communication.
Interestingly, specific miRNAs are enriched in exosomes in a cell-type-dependent fashion …
Interestingly, specific miRNAs are enriched in exosomes in a cell-type-dependent fashion …
Gene silencing by microRNAs: contributions of translational repression and mRNA decay
E Huntzinger, E Izaurralde - Nature Reviews Genetics, 2011 - nature.com
Despite their widespread roles as regulators of gene expression, important questions
remain about target regulation by microRNAs. Animal microRNAs were originally thought to …
remain about target regulation by microRNAs. Animal microRNAs were originally thought to …
MicroRNA: biogenesis, function and role in cancer
LA MacFarlane, PR Murphy - Current genomics, 2010 - ingentaconnect.com
MicroRNAs are small, highly conserved non-coding RNA molecules involved in the
regulation of gene expression. MicroRNAs are transcribed by RNA polymerases II and III …
regulation of gene expression. MicroRNAs are transcribed by RNA polymerases II and III …
Phase transitions in the assembly and function of human miRISC
J Sheu-Gruttadauria, IJ MacRae - Cell, 2018 - cell.com
Summary miRISC is a multi-protein assembly that uses microRNAs (miRNAs) to identify
mRNAs targeted for repression. Dozens of miRISC-associated proteins have been …
mRNAs targeted for repression. Dozens of miRISC-associated proteins have been …
RISC assembly: Coordination between small RNAs and Argonaute proteins
H Kobayashi, Y Tomari - Biochimica et Biophysica Acta (BBA)-Gene …, 2016 - Elsevier
Non-coding RNAs generally form ribonucleoprotein (RNP) complexes with their partner
proteins to exert their functions. Small RNAs, including microRNAs, small interfering RNAs …
proteins to exert their functions. Small RNAs, including microRNAs, small interfering RNAs …
[HTML][HTML] Origins and mechanisms of miRNAs and siRNAs
RW Carthew, EJ Sontheimer - Cell, 2009 - cell.com
Over the last decade,∼ 20–30 nucleotide RNA molecules have emerged as critical
regulators in the expression and function of eukaryotic genomes. Two primary categories of …
regulators in the expression and function of eukaryotic genomes. Two primary categories of …