Therapeutic monoclonal antibodies (mAbs) are the fastest growing class of new therapeutic
molecules. They hold great promises for the treatment of a variety of diseases, including …

Recombinant monoclonal antibodies (mAbs) are one of today's most successful therapeutic
classes in inflammatory diseases and oncology. A wider accessibility and implementation …

The use of replicating viruses for cancer therapy (virotherapy) holds much promise. We
reported previously that the live attenuated Edmonston B vaccine strain of measles virus …

The emergence of recombinant technologies has revolutionized the selection and
production of monoclonal antibodies, allowing the design of fully human antibodies of any …

A key feature of antibodies is their ability to bind antigens with high specificity and affinity.
This has led to the concept of intracellular antibodies (intrabodies), designed to mimic …

Induction of apoptosis in cancer cells has increasingly been the focus of many therapeutic
approaches in oncology field. Since its identification as a TNF family member, TRAIL (TNF …

Definitive treatment of cancer has eluded scientists for decades. Current therapeutic
modalities like surgery, chemotherapy, radiotherapy and receptor-targeted antibodies have …

Our knowledge of tumor immunology has resulted in multiple approaches for the treatment
of cancer. However, a gap between research of new tumors markers and development of …

Antibody‐based therapeutics are beginning to realize the promise enclosed in their early
denomination as “magic bullets”. Initial disappointment has turned into clinical and …

Transmissible spongiform encephalopathies are a group of neurological disorders
associated with the deposition of PrPSc, an abnormal form of the cellular prion protein PrPc …