The genetics of multiple sclerosis: from 0 to 200 in 50 years
SE Baranzini, JR Oksenberg - Trends in genetics, 2017 - cell.com
Multiple sclerosis (MS) is a common autoimmune disease that targets myelin in the central
nervous system (CNS). Multiple genome-wide association studies (GWAS) over the past 10 …
nervous system (CNS). Multiple genome-wide association studies (GWAS) over the past 10 …
The genetics of multiple sclerosis: an up‐to‐date review
Multiple sclerosis (MS) is a prevalent inflammatory disease of the central nervous system
that often leads to disability in young adults. Treatment options are limited and often only …
that often leads to disability in young adults. Treatment options are limited and often only …
Axonal transection in the lesions of multiple sclerosis
BD Trapp, J Peterson, RM Ransohoff… - … England Journal of …, 1998 - Mass Medical Soc
Background Multiple sclerosis is an inflammatory demyelinating disease of the central
nervous system and is the most common cause of neurologic disability in young adults …
nervous system and is the most common cause of neurologic disability in young adults …
Heterogeneity of multiple sclerosis lesions: implications for the pathogenesis of demyelination
C Lucchinetti, W Brück, J Parisi… - Annals of Neurology …, 2000 - Wiley Online Library
Multiple sclerosis (MS) is a disease with profound heterogeneity in clinical course,
neuroradiological appearance of the lesions, involvement of susceptibility gene loci, and …
neuroradiological appearance of the lesions, involvement of susceptibility gene loci, and …
Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis
Microarray analysis of multiple sclerosis (MS) lesions obtained at autopsy revealed
increased transcripts of genes encoding inflammatory cytokines, particularly interleukin-6 …
increased transcripts of genes encoding inflammatory cytokines, particularly interleukin-6 …
Risk alleles for multiple sclerosis identified by a genomewide study
International Multiple Sclerosis Genetics … - New England Journal …, 2007 - Mass Medical Soc
Background Multiple sclerosis has a clinically significant heritable component. We
conducted a genomewide association study to identify alleles associated with the risk of …
conducted a genomewide association study to identify alleles associated with the risk of …
The influence of the proinflammatory cytokine, osteopontin, on autoimmune demyelinating disease
D Chabas, SE Baranzini, D Mitchell, CCA Bernard… - Science, 2001 - science.org
Multiple sclerosis is a demyelinating disease, characterized by inflammation in the brain and
spinal cord, possibly due to autoimmunity. Large-scale sequencing of cDNA libraries …
spinal cord, possibly due to autoimmunity. Large-scale sequencing of cDNA libraries …
Genetics of multiple sclerosis
Multiple sclerosis (MS) is probably aetiologically heterogeneous. Systematic genetic
epidemiological and molecular genetic studies have provided important insights. Both …
epidemiological and molecular genetic studies have provided important insights. Both …
Multiple sclerosis: a two-stage disease
L Steinman - Nature immunology, 2001 - nature.com
Multiple sclerosis: a two-stage disease | Nature Immunology Skip to main content Thank you
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for visiting nature.com. You are using a browser version with limited support for CSS. To obtain …
A Pathogenic Role for Myelin-Specific Cd8+ T Cells in a Model for Multiple Sclerosis
ES Huseby, D Liggitt, T Brabb, B Schnabel… - The Journal of …, 2001 - rupress.org
Multiple sclerosis (MS) is a demyelinating disease of the central nervous system (CNS)
characterized by plaques of infiltrating CD4+ and CD8+ T cells. Studies of MS and …
characterized by plaques of infiltrating CD4+ and CD8+ T cells. Studies of MS and …