Clinical interpretation of whole-genome and whole-transcriptome sequencing for precision oncology

V Jobanputra, KO Wrzeszczynski, R Buttner… - Seminars in Cancer …, 2022 - Elsevier
Whole-genome sequencing either alone or in combination with whole-transcriptome
sequencing has started to be used to analyze clinical tumor samples to improve diagnosis …

An Overview of Advances in Rare Cancer Diagnosis and Treatment

G Christyani, M Carswell, S Qin, W Kim - International Journal of …, 2024 - mdpi.com
Cancer stands as the leading global cause of mortality, with rare cancer comprising 230
distinct subtypes characterized by infrequent incidence. Despite the inherent challenges in …

Cancer informatics for cancer centers: Scientific drivers for informatics, data science, and care in pediatric, adolescent, and young adult cancer

AR Kerlavage, AC Kirchhoff, JM Guidry Auvil… - JCO clinical cancer …, 2021 - ascopubs.org
Cancer Informatics for Cancer Centers (CI4CC) is a grassroots, nonprofit 501c3 organization
intended to provide a focused national forum for engagement of senior cancer informatics …

Comparative analysis of RNA expression in a single institution cohort of pediatric cancer patients

Y Vasquez, H Beale, L Sanders, AG Lyle, ET Kephart… - medRxiv, 2024 - medrxiv.org
Importance Genomic analyses solely focused on detecting mutations do not benefit most
pediatric cancer patients. Alternate genomic approaches are needed to identify additional …

[图书][B] Multi-omic Analyses and Organoid Models for Identification of Therapeutic Vulnerabilities and Developmental Origins in Childhood Cancer

LM Sanders - 2020 - search.proquest.com
Pediatric cancers are different from adult cancers in that they often have few targetable DNA
mutations, and in most cases are thought to be developmental in origin rather than …