[HTML][HTML] Early diagnosis and prevention of infections in cirrhosis

AV Kulkarni, M Premkumar, JP Arab… - Seminars in Liver …, 2022 - thieme-connect.com
Strategies to prevent infection and improve outcomes in patients with cirrhosis. HAV,
hepatitis A virus; HBV, hepatitis B virus; COVID-19, novel coronavirus disease 2019; NSBB …

Potential therapies for acute‐on‐chronic liver failure

MA Morrison, F Artru, FM Trovato… - Liver …, 2023 - Wiley Online Library
Acute‐on‐chronic liver failure (ACLF) is a syndrome that develops in approximately 30% of
patients hospitalised with cirrhosis and is characterised by an acute decompensation of liver …

[HTML][HTML] Atorvastatin for patients with cirrhosis. A randomized, placebo-controlled trial

TM Kronborg, R Schierwagen, K Trošt… - Hepatology …, 2023 - journals.lww.com
Background: Patients with cirrhosis and portal hypertension face a high risk of
complications. Besides their anti-inflammatory and antifibrotic effects, statins may reduce …

Emerging role of statin therapy in the prevention and management of cirrhosis, portal hypertension, and HCC

SR Sharpton, R Loomba - Hepatology, 2023 - journals.lww.com
Statins, the most widely used lipid-lowering drugs, are increasingly recognized to have
pleiotropic effects including anti-inflammatory and antiangiogenic properties as well as …

Current challenges and future perspectives in treating patients with NAFLD-related cirrhosis

M Mallet, CA Silaghi, P Sultanik, F Conti, M Rudler… - Hepatology, 2024 - journals.lww.com
Despite the slow, progressive nature of NAFLD, the number of patients with NAFLD-related
cirrhosis has significantly increased. Although the management of patients with cirrhosis is …

Pathophysiology and management of liver cirrhosis: from portal hypertension to acute-on-chronic liver failure

RK Jagdish, A Roy, K Kumar, M Premkumar… - Frontiers in …, 2023 - frontiersin.org
Cirrhosis transcends various progressive stages from compensation to decompensation
driven by the severity of portal hypertension. The downstream effect of increasing portal …

Review of the role of statins in cirrhosis and portal hypertension

J Gratacós-Ginès, E Pose - Clinical liver disease, 2023 - journals.lww.com
Statins are a group of molecules that inhibit the activity of hydroxymethylglutaryl (HMG-CoA)
reductase, lowering cholesterol levels. Besides their lipid-lowering effect, statins have also …

Liver transplantation in acute-on-chronic liver failure

AV Kulkarni, KR Reddy - Clinics in Liver Disease, 2023 - liver.theclinics.com
Acute-on-chronic liver failure (ACLF) is a form of acute and advanced liver failure in patients
with underlying chronic liver disease and is associated with nonhepatic organ failures and …

Recent advances in the prevention and treatment of decompensated cirrhosis and acute-on-chronic liver failure (ACLF) and the role of biomarkers

J Trebicka, R Hernaez, DL Shawcross, AL Gerbes - Gut, 2024 - gut.bmj.com
The progression of cirrhosis with clinically significant portal hypertension towards
decompensated cirrhosis remains clinically challenging and the evolution towards acute-on …

Type of infection is associated with prognosis in acute-on-chronic liver failure: a National Veterans Health Administration Study

N Mahmud, KR Reddy, TH Taddei… - Digestive diseases and …, 2023 - Springer
Background Acute-on-chronic liver failure (ACLF) is a syndrome in patients with cirrhosis
with high short-term mortality. Infection is a frequent precipitant of ACLF; however, it is …