The blood–retina barrier in health and disease
F O'Leary, M Campbell - The FEBS journal, 2023 - Wiley Online Library
The blood–retina barrier (BRB) is the term used to define the properties of the retinal
capillaries and the retinal pigment epithelium (RPE), which separate the systemic circulation …
capillaries and the retinal pigment epithelium (RPE), which separate the systemic circulation …
Prevention of microvascular complications of diabetes
Global prevalence estimates from 2019 suggest that the number of people diagnosed with
diabetes was 463 million and is projected to increase to 700 million by the year 2045. 1 The …
diabetes was 463 million and is projected to increase to 700 million by the year 2045. 1 The …
The innate immune system in diabetic retinopathy
WW Pan, F Lin, PE Fort - Progress in retinal and eye research, 2021 - Elsevier
The prevalence of diabetes has been rising steadily in the past half-century, along with the
burden of its associated complications, including diabetic retinopathy (DR). DR is currently …
burden of its associated complications, including diabetic retinopathy (DR). DR is currently …
[HTML][HTML] Diabetic retinopathy for the non-ophthalmologist
THM Fung, B Patel, EG Wilmot, WMK Amoaku - Clinical Medicine, 2022 - Elsevier
Diabetic retinopathy is a microangiopathy resulting from the chronic effects of diabetes
mellitus. Healthcare professionals often work in isolation to deliver highly specialised care …
mellitus. Healthcare professionals often work in isolation to deliver highly specialised care …
The role of intravitreal corticosteroids in the treatment of DME: predictive OCT biomarkers
This work aims to summarize predictive biomarkers to guide treatment choice in DME.
Intravitreal anti-VEGF is considered the gold standard treatment for centers involving DME …
Intravitreal anti-VEGF is considered the gold standard treatment for centers involving DME …
[HTML][HTML] TXNIP positively regulates the autophagy and apoptosis in the rat müller cell of diabetic retinopathy
H Ao, H Li, X Zhao, B Liu, L Lu - Life sciences, 2021 - Elsevier
Aims Diabetic retinopathy (DR) can cause vision loss in patients with diabetes. The present
study evaluated the expression of thioredoxin interacting protein (TXNIP) and investigated …
study evaluated the expression of thioredoxin interacting protein (TXNIP) and investigated …
Oxidative stress, inflammatory, angiogenic, and apoptotic molecules in proliferative diabetic retinopathy and diabetic macular edema patients
I Andrés-Blasco, A Gallego-Martínez… - International journal of …, 2023 - mdpi.com
The aim of this study is to evaluate molecules involved in oxidative stress (OS),
inflammation, angiogenesis, and apoptosis, and discern which of these are more likely to be …
inflammation, angiogenesis, and apoptosis, and discern which of these are more likely to be …
In-depth transcriptomic analysis of human retina reveals molecular mechanisms underlying diabetic retinopathy
K Becker, H Klein, E Simon, C Viollet, C Haslinger… - Scientific reports, 2021 - nature.com
Diabetic Retinopathy (DR) is among the major global causes for vision loss. With the rise in
diabetes prevalence, an increase in DR incidence is expected. Current understanding of …
diabetes prevalence, an increase in DR incidence is expected. Current understanding of …
Molecular investigation of candidate genes for pyroptosis-induced inflammation in diabetic retinopathy
N Wang, L Ding, D Liu, Q Zhang, G Zheng… - Frontiers in …, 2022 - frontiersin.org
Background Diabetic retinopathy is a diabetic microvascular complication. Pyroptosis, as a
way of inflammatory death, plays an important role in the occurrence and development of …
way of inflammatory death, plays an important role in the occurrence and development of …
LRG1 as a novel therapeutic target in eye disease
Retinal and choroidal diseases are major causes of blindness and visual impairment in the
developed world and on the rise due to an ageing population and diabetes epidemic …
developed world and on the rise due to an ageing population and diabetes epidemic …