The core pathology of coronavirus disease 2019 (COVID-19) is infection of airway cells by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that results in excessive …

Platelets are abundant, small, anucleate circulating cells, serving many emerging
pathophysiological roles beyond hemostasis; including active critical roles in thrombosis …

Current understanding of tumor immunosuppressive mechanisms forms the basis for
modern day immunotherapies. Immunoregulatory role of platelets in cancer remains largely …

Platelets have been shown to be associated with pathophysiological processes beyond
thrombosis, demonstrating critical additional roles in homeostatic processes, such as …

Aging is associated with an increased incidence of cardiovascular disease and thrombosis.
Platelets play a major role in maintaining hemostasis and in thrombus formation, making …

Thrombosis is a common disorder with a relevant burden of morbidity and mortality
worldwide, particularly among elderly patients. Growing evidence demonstrated a direct role …

The goal of this review article is to provide a resource for longitudinal studies, using animal
models, directed at understanding and modifying the relationship between cognition and …

Background: Unfolded protein response (UPR) is a multifaceted signaling cascade that
alleviates protein misfolding. Although well studied in nucleated cells, UPR in absence of …

Background: Reactive oxygen species (ROS) contribute to platelet hyperactivation during
aging. Several oxidative pathways and antioxidant enzymes have been implicated; …

Cardiovascular disorders (CVD) are highly prevalent and the leading cause of death
worldwide. Atherosclerosis is responsible for most cases of CVD. The plaque formation and …