An estimated 20% of all patients with cancer will develop brain metastases, with the majority
of brain metastases occurring in those with lung, breast and colorectal cancers, melanoma …

Metallothioneins (MTs) are small cysteine-rich proteins that play important roles in metal
homeostasis and protection against heavy metal toxicity, DNA damage, and oxidative stress …

Purpose: This AUA Guideline focuses on evaluation/counseling and management of adult
patients with clinically localized renal masses suspicious for cancer, including solid …

The therapeutic targeting of extracellular proteins is becoming hugely attractive in light of
evidence implicating the tumour microenvironment as pivotal in all aspects of tumour …

This 2004 volume in the World Health Organization series on histologic and genetic typing
of human tumors covers tumors of the kidney, urinary system, prostate, testis and …

ABSTRACT Every year the American Cancer Society estimates the number of new cancer
cases and deaths expected in the United States in the current year and compiles the most …

Abstract Renal Cell Carcinoma (RCC) has the highest mortality rate of the genitourinary
cancers and the incidence of RCC has risen steadily. If detected early, RCC is curable by …

Identifying tumor-cell-specific markers and elucidating their epigenetic regulation and spatial
heterogeneity provides mechanistic insights into cancer etiology. Here, we perform snRNA …

The increasing availability and maturity of DNA microarray technology has led to an
explosion of cancer profiling studies. To extract maximum value from the accumulating mass …

Clear cell renal cell carcinoma (ccRCC) is the predominant RCC subtype, but even within
this classification, the natural history is heterogeneous and difficult to predict. A sophisticated …